Chimeric autoantibody receptor T cells clonally eliminate B cells producing autoantibodies against IFN-γ.
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| Title: | Chimeric autoantibody receptor T cells clonally eliminate B cells producing autoantibodies against IFN-γ. |
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| Authors: | Peng JJ; Center for Molecular and Clinical Immunology, Chang Gung University, Taoyuan, Taiwan.; Laboratory of Human Immunology and Infectious Diseases, Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan, Taiwan.; Ludwig Institute of Cancer Research, University of Lausanne, Lausanne, Switzerland.; Department of Fundamental Oncology, University of Lausanne, Lausanne, Switzerland., Ding JY; Center for Molecular and Clinical Immunology, Chang Gung University, Taoyuan, Taiwan.; Laboratory of Human Immunology and Infectious Diseases, Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan, Taiwan., Xu Y; Ludwig Institute of Cancer Research, University of Lausanne, Lausanne, Switzerland.; Department of Fundamental Oncology, University of Lausanne, Lausanne, Switzerland., Shih HP; Center for Molecular and Clinical Immunology, Chang Gung University, Taoyuan, Taiwan.; Laboratory of Human Immunology and Infectious Diseases, Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan, Taiwan., Lin YN; Center for Molecular and Clinical Immunology, Chang Gung University, Taoyuan, Taiwan.; Laboratory of Human Immunology and Infectious Diseases, Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan, Taiwan., Wu TY; Center for Molecular and Clinical Immunology, Chang Gung University, Taoyuan, Taiwan.; Laboratory of Human Immunology and Infectious Diseases, Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan, Taiwan., Lo YF; Center for Molecular and Clinical Immunology, Chang Gung University, Taoyuan, Taiwan.; Laboratory of Human Immunology and Infectious Diseases, Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan, Taiwan., Lo CC; Center for Molecular and Clinical Immunology, Chang Gung University, Taoyuan, Taiwan.; Laboratory of Human Immunology and Infectious Diseases, Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan, Taiwan., Yeh CF; Laboratory of Human Immunology and Infectious Diseases, Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan, Taiwan.; Division of Infectious Diseases, Department of Internal Medicine, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan., Kuo CY; Laboratory of Human Immunology and Infectious Diseases, Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan, Taiwan.; Division of Infectious Diseases, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan.; School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan., Tu KH; Center for Molecular and Clinical Immunology, Chang Gung University, Taoyuan, Taiwan.; Department of Nephrology, Chang Gung Memorial Hospital, Taoyuan, Taiwan., Wang SY; Laboratory of Human Immunology and Infectious Diseases, Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan, Taiwan.; Division of General Surgery, Department of Surgery, Chang Gung Memorial Hospital, Taoyuan, Taiwan., Lei WT; Laboratory of Human Immunology and Infectious Diseases, Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan, Taiwan.; Department of Pediatrics, Division of Pediatric Allergy, Immunology, and Rheumatology, Hsinchu Municipal MacKay Children's Hospital, Hsinchu, Taiwan., Wu TS; Division of Infectious Diseases, Department of Internal Medicine, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.; School of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan., Lin HS; Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital, Chiayi, Taiwan., Lee CH; Division of Infectious Diseases, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan., Huang WC; Division of Infectious Diseases, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan., Chen YC; Division of Infectious Diseases, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan., Liu YM; Division of Infectious Diseases, Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan., Shi ZY; Division of Infectious Diseases, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan., Chang YT; Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan., Syue LS; Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Chen PL; Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Teh SH; Division of Infectious Diseases, Department of Internal Medicine, Hualien Tzu Chi Hospital, Hualien, Taiwan., Chou CH; Division of Infectious Diseases, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.; School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan., Ho MW; Division of Infectious Diseases, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.; School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan., Chi CY; Division of Infectious Diseases, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.; School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan., Ho PC; Ludwig Institute of Cancer Research, University of Lausanne, Lausanne, Switzerland.; Department of Fundamental Oncology, University of Lausanne, Lausanne, Switzerland., Ku CL; Center for Molecular and Clinical Immunology, Chang Gung University, Taoyuan, Taiwan.; Laboratory of Human Immunology and Infectious Diseases, Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan, Taiwan.; Division of Infectious Diseases, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan.; Department of Nephrology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.; Elixiron Immunotherapeutics, Taipei, Taiwan. |
| Source: | Science immunology [Sci Immunol] 2025 May 09; Vol. 10 (107), pp. eadm8186. Date of Electronic Publication: 2025 May 09. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101688624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2470-9468 (Electronic) Linking ISSN: 24709468 NLM ISO Abbreviation: Sci Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2470-9468 |
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| DOI: | 10.1126/sciimmunol.adm8186 |
