T cell memory response to MPXV infection exhibits greater effector function and migratory potential compared to MVA-BN vaccination.
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| Title: | T cell memory response to MPXV infection exhibits greater effector function and migratory potential compared to MVA-BN vaccination. |
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| Authors: | Chen JL; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.; MRC Translational Immune Discovery Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Wang B; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK., Lu Y; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., Antoun E; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.; Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Bird O; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Drennan PG; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Medicine, University of Oxford, Oxford, UK., Yin Z; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK., Liu G; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK., Yao X; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK., Pidoux M; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.; MRC Translational Immune Discovery Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Bates A; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.; MRC Translational Immune Discovery Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Jayathilaka D; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.; MRC Translational Immune Discovery Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Wang J; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.; MRC Translational Immune Discovery Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Angus B; NDM Centre for Global Health Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Beer S; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Espinosa A; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Baillie JK; Baillie Gifford Pandemic Science Hub, Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK.; Roslin Institute, University of Edinburgh, Easter Bush, Midlothian, Edinburgh, UK.; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh, UK.; Intensive Care Unit, Royal Infirmary Edinburgh, Edinburgh, UK., Semple MG; NIHR Health Protection Research Unit, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK., Rostron T; Sequencing Facility, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Waugh C; Flow Cytometry Facility, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Sopp P; Flow Cytometry Facility, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Knight JC; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.; Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Fullerton JN; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Botnar Institute for Musculoskeletal Sciences, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Medicine, University of Oxford, Oxford, UK., Coles M; Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Medicine, University of Oxford, Oxford, UK., Smith GL; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.; MRC Translational Immune Discovery Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., Mentzer AJ; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.; Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Peng Y; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.; MRC Translational Immune Discovery Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Dong T; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK. tao.dong@ndm.ox.ac.uk.; MRC Translational Immune Discovery Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK. tao.dong@ndm.ox.ac.uk. |
| Corporate Authors: | ISARIC4C Investigators |
| Source: | Nature communications [Nat Commun] 2025 May 10; Vol. 16 (1), pp. 4362. Date of Electronic Publication: 2025 May 10. |
| Publication Type: | Journal Article; Comparative Study |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-59370-5 |
