Taurine from tumour niche drives glycolysis to promote leukaemogenesis.

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Title: Taurine from tumour niche drives glycolysis to promote leukaemogenesis.
Authors: Sharma S; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY, USA.; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA., Rodems BJ; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY, USA.; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA., Baker CD; Genomics Research Center, University of Rochester Medical Center, Rochester, NY, USA., Kaszuba CM; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.; Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA., Franco EI; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.; Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA., Smith BR; Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, NY, USA., Ito T; Department of Bioscience and Technology, Graduate School of Bioscience and Technology, Fukui Prefectural University, Fukui, Japan., Swovick K; Mass Spectrometry Resource Laboratory, University of Rochester, Rochester, NY, USA., Welle K; Mass Spectrometry Resource Laboratory, University of Rochester, Rochester, NY, USA., Zhang Y; Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, USA., Rock P; Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, USA., Chaves FA; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA., Ghaemmaghami S; Mass Spectrometry Resource Laboratory, University of Rochester, Rochester, NY, USA.; Department of Biology, University of Rochester, Rochester, NY, USA., Calvi LM; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.; Department of Medicine, University of Rochester Medical Center, Rochester, NY, USA., Ganguly A; Department of Neuroscience, University of Rochester Medical Center, Rochester, NY, USA., Burack WR; Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, USA., Becker MW; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.; Department of Medicine, University of Rochester Medical Center, Rochester, NY, USA., Liesveld JL; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.; Department of Medicine, University of Rochester Medical Center, Rochester, NY, USA., Brookes PS; Department of Anesthesiology, University of Rochester Medical Center, Rochester, NY, USA., Munger JC; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.; Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, NY, USA., Jordan CT; Division of Hematology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Ashton JM; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY, USA.; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.; Genomics Research Center, University of Rochester Medical Center, Rochester, NY, USA., Bajaj J; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY, USA. Jeevisha_Bajaj@URMC.Rochester.edu.; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA. Jeevisha_Bajaj@URMC.Rochester.edu.
Source: Nature [Nature] 2025 Aug; Vol. 644 (8075), pp. 263-272. Date of Electronic Publication: 2025 May 14.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-4687
DOI:10.1038/s41586-025-09018-7