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Taurine from tumour niche drives glycolysis to promote leukaemogenesis.

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Title: Taurine from tumour niche drives glycolysis to promote leukaemogenesis.
Authors: Sharma S; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY, USA.; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA., Rodems BJ; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY, USA.; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA., Baker CD; Genomics Research Center, University of Rochester Medical Center, Rochester, NY, USA., Kaszuba CM; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.; Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA., Franco EI; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.; Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA., Smith BR; Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, NY, USA., Ito T; Department of Bioscience and Technology, Graduate School of Bioscience and Technology, Fukui Prefectural University, Fukui, Japan., Swovick K; Mass Spectrometry Resource Laboratory, University of Rochester, Rochester, NY, USA., Welle K; Mass Spectrometry Resource Laboratory, University of Rochester, Rochester, NY, USA., Zhang Y; Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, USA., Rock P; Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, USA., Chaves FA; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA., Ghaemmaghami S; Mass Spectrometry Resource Laboratory, University of Rochester, Rochester, NY, USA.; Department of Biology, University of Rochester, Rochester, NY, USA., Calvi LM; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.; Department of Medicine, University of Rochester Medical Center, Rochester, NY, USA., Ganguly A; Department of Neuroscience, University of Rochester Medical Center, Rochester, NY, USA., Burack WR; Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, USA., Becker MW; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.; Department of Medicine, University of Rochester Medical Center, Rochester, NY, USA., Liesveld JL; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.; Department of Medicine, University of Rochester Medical Center, Rochester, NY, USA., Brookes PS; Department of Anesthesiology, University of Rochester Medical Center, Rochester, NY, USA., Munger JC; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.; Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, NY, USA., Jordan CT; Division of Hematology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Ashton JM; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY, USA.; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.; Genomics Research Center, University of Rochester Medical Center, Rochester, NY, USA., Bajaj J; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY, USA. Jeevisha_Bajaj@URMC.Rochester.edu.; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA. Jeevisha_Bajaj@URMC.Rochester.edu.
Source: Nature [Nature] 2025 Aug; Vol. 644 (8075), pp. 263-272. Date of Electronic Publication: 2025 May 14.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
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  Data: Taurine from tumour niche drives glycolysis to promote leukaemogenesis.
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  Data: <searchLink fieldCode="AU" term="%22Sharma+S%22">Sharma S</searchLink>; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY, USA.; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.<br /><searchLink fieldCode="AU" term="%22Rodems+BJ%22">Rodems BJ</searchLink>; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY, USA.; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.<br /><searchLink fieldCode="AU" term="%22Baker+CD%22">Baker CD</searchLink>; Genomics Research Center, University of Rochester Medical Center, Rochester, NY, USA.<br /><searchLink fieldCode="AU" term="%22Kaszuba+CM%22">Kaszuba CM</searchLink>; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.; Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA.<br /><searchLink fieldCode="AU" term="%22Franco+EI%22">Franco EI</searchLink>; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.; Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA.<br /><searchLink fieldCode="AU" term="%22Smith+BR%22">Smith BR</searchLink>; Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ito+T%22">Ito T</searchLink>; Department of Bioscience and Technology, Graduate School of Bioscience and Technology, Fukui Prefectural University, Fukui, Japan.<br /><searchLink fieldCode="AU" term="%22Swovick+K%22">Swovick K</searchLink>; Mass Spectrometry Resource Laboratory, University of Rochester, Rochester, NY, USA.<br /><searchLink fieldCode="AU" term="%22Welle+K%22">Welle K</searchLink>; Mass Spectrometry Resource Laboratory, University of Rochester, Rochester, NY, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, USA.<br /><searchLink fieldCode="AU" term="%22Rock+P%22">Rock P</searchLink>; Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, USA.<br /><searchLink fieldCode="AU" term="%22Chaves+FA%22">Chaves FA</searchLink>; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ghaemmaghami+S%22">Ghaemmaghami S</searchLink>; Mass Spectrometry Resource Laboratory, University of Rochester, Rochester, NY, USA.; Department of Biology, University of Rochester, Rochester, NY, USA.<br /><searchLink fieldCode="AU" term="%22Calvi+LM%22">Calvi LM</searchLink>; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.; Department of Medicine, University of Rochester Medical Center, Rochester, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ganguly+A%22">Ganguly A</searchLink>; Department of Neuroscience, University of Rochester Medical Center, Rochester, NY, USA.<br /><searchLink fieldCode="AU" term="%22Burack+WR%22">Burack WR</searchLink>; Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, USA.<br /><searchLink fieldCode="AU" term="%22Becker+MW%22">Becker MW</searchLink>; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.; Department of Medicine, University of Rochester Medical Center, Rochester, NY, USA.<br /><searchLink fieldCode="AU" term="%22Liesveld+JL%22">Liesveld JL</searchLink>; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.; Department of Medicine, University of Rochester Medical Center, Rochester, NY, USA.<br /><searchLink fieldCode="AU" term="%22Brookes+PS%22">Brookes PS</searchLink>; Department of Anesthesiology, University of Rochester Medical Center, Rochester, NY, USA.<br /><searchLink fieldCode="AU" term="%22Munger+JC%22">Munger JC</searchLink>; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.; Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, NY, USA.<br /><searchLink fieldCode="AU" term="%22Jordan+CT%22">Jordan CT</searchLink>; Division of Hematology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Ashton+JM%22">Ashton JM</searchLink>; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY, USA.; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.; Genomics Research Center, University of Rochester Medical Center, Rochester, NY, USA.<br /><searchLink fieldCode="AU" term="%22Bajaj+J%22">Bajaj J</searchLink>; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY, USA. Jeevisha_Bajaj@URMC.Rochester.edu.; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA. Jeevisha_Bajaj@URMC.Rochester.edu.
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  Data: <searchLink fieldCode="JN" term="%220410462%22">Nature</searchLink> [Nature] 2025 Aug; Vol. 644 (8075), pp. 263-272. <i>Date of Electronic Publication: </i>2025 May 14.
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