Network pharmacology and experimental validation to investigate the mechanism of action of Zhilong Huoxue Tongyu capsule in the prevention and treatment of diabetic cardiomyopathy.

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Title: Network pharmacology and experimental validation to investigate the mechanism of action of Zhilong Huoxue Tongyu capsule in the prevention and treatment of diabetic cardiomyopathy.
Authors: Yang F; National Traditional Chinese Medicine Clinical Research Base and Cardiology department of the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China.; Institute of Integrated Chinese and Western Medicine, Southwest Medical University, Luzhou, China., Luo G; National Traditional Chinese Medicine Clinical Research Base and Cardiology department of the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China.; Institute of Integrated Chinese and Western Medicine, Southwest Medical University, Luzhou, China., Liu MN; National Traditional Chinese Medicine Clinical Research Base and Cardiology department of the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China.; Institute of Integrated Chinese and Western Medicine, Southwest Medical University, Luzhou, China., Liu P; National Traditional Chinese Medicine Clinical Research Base and Cardiology department of the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China.; Institute of Integrated Chinese and Western Medicine, Southwest Medical University, Luzhou, China., Wu D; National Traditional Chinese Medicine Clinical Research Base and Cardiology department of the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China.; Institute of Integrated Chinese and Western Medicine, Southwest Medical University, Luzhou, China., Chen HL; National Traditional Chinese Medicine Clinical Research Base and Cardiology department of the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China.; Institute of Integrated Chinese and Western Medicine, Southwest Medical University, Luzhou, China., Li S; National Traditional Chinese Medicine Clinical Research Base and Cardiology department of the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China.; Institute of Integrated Chinese and Western Medicine, Southwest Medical University, Luzhou, China., Yang SJ; National Traditional Chinese Medicine Clinical Research Base and Cardiology department of the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China.; Institute of Integrated Chinese and Western Medicine, Southwest Medical University, Luzhou, China., Dong L; National Traditional Chinese Medicine Clinical Research Base and Cardiology department of the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China.; Institute of Integrated Chinese and Western Medicine, Southwest Medical University, Luzhou, China.
Source: PloS one [PLoS One] 2025 May 15; Vol. 20 (5), pp. e0323745. Date of Electronic Publication: 2025 May 15 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1932-6203
DOI:10.1371/journal.pone.0323745