Genomic and transcriptomic determinants of clinical outcomes in patients with AML and DNMT3A mutations.

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Title: Genomic and transcriptomic determinants of clinical outcomes in patients with AML and DNMT3A mutations.
Authors: Ni SC; Department of Hematological Oncology, National Taiwan University Cancer Center, Taipei, Taiwan., Yao CY; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.; Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan., Tsai XC; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan., Lo MY; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital Yunlin Branch, Yunlin, Taiwan., Chen CY; Department of Internal Medicine, National Taiwan University Hospital, Hsin-Chu Branch, Hsin-Chu, Taiwan., Lee WH; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.; Department of Internal Medicine, National Taiwan University Hospital, Hsin-Chu Branch, Hsin-Chu, Taiwan., Lin CC; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan., Kuo YY; Tai-Chen Cell Therapy Center, National Taiwan University, Taipei, Taiwan., Peng YL; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan., Tseng MH; Tai-Chen Cell Therapy Center, National Taiwan University, Taipei, Taiwan., Wu YS; Department of Nursing, National Taiwan University Hospital, Taipei, Taiwan., Liu MC; Department of Pathology, National Taiwan University Hospital, Taipei, Taiwan., Lin LI; Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan., Chuang MK; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan., Ko BS; Department of Hematological Oncology, National Taiwan University Cancer Center, Taipei, Taiwan.; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan., Yao M; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan., Tang JL; Department of Hematological Oncology, National Taiwan University Cancer Center, Taipei, Taiwan.; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Tai-Chen Cell Therapy Center, National Taiwan University, Taipei, Taiwan., Tien FM; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan. b92401007@ntu.edu.tw.; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan. b92401007@ntu.edu.tw., Chou WC; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan., Hou HA; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Division of General Medicine, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan., Tien HF; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Internal Medicine, Far-Eastern Memorial Hospital, New Taipei City, Taiwan.
Source: Blood cancer journal [Blood Cancer J] 2025 May 20; Vol. 15 (1), pp. 97. Date of Electronic Publication: 2025 May 20.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101568469 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-5385 (Electronic) Linking ISSN: 20445385 NLM ISO Abbreviation: Blood Cancer J Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2044-5385
DOI:10.1038/s41408-025-01287-9