hiPSC-neurons recapitulate the subtype-specific cell intrinsic nature of susceptibility to neurodegenerative disease-relevant aggregation.

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Title: hiPSC-neurons recapitulate the subtype-specific cell intrinsic nature of susceptibility to neurodegenerative disease-relevant aggregation.
Authors: Weidling I; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA., Preiss CN; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA., Chancellor SE; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA., Srivastava G; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA., Gibilisco L; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA., Lin G; AbbVie Pte Ltd, 9 North Buona Vista Drive #19-01, Singapore, 138588, Singapore., Brennan MS; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA., Lee J; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA., Roth LM; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA., Morozova O; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA., Nam KN; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA., Patel NR; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA., Liu Q; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA., Thomas JK; AbbVie, Chicago, USA., Reinhardt P; AbbVie Deutschland GmbH & Co. KG, 67061, Ludwigshafen, Germany., Wilkens R; AbbVie Deutschland GmbH & Co. KG, 67061, Ludwigshafen, Germany., Ehrnhoefer DE; AbbVie Deutschland GmbH & Co. KG, 67061, Ludwigshafen, Germany., Striebinger A; AbbVie Deutschland GmbH & Co. KG, 67061, Ludwigshafen, Germany., Barghorn S; AbbVie Deutschland GmbH & Co. KG, 67061, Ludwigshafen, Germany., Xanthopoulos C; AbbVie Deutschland GmbH & Co. KG, 67061, Ludwigshafen, Germany., Weil MT; AbbVie Deutschland GmbH & Co. KG, 67061, Ludwigshafen, Germany., Biesinger S; AbbVie Deutschland GmbH & Co. KG, 67061, Ludwigshafen, Germany., Cik M; AbbVie Deutschland GmbH & Co. KG, 67061, Ludwigshafen, Germany., Romanul N; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA., Yanamandra K; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA., Welker AM; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA., Wu J; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA., Gasparini L; AbbVie Deutschland GmbH & Co. KG, 67061, Ludwigshafen, Germany., Stöhr J; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA., Langlois X; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA., Manos JD; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA. justine.manos@abbvie.com.
Source: Acta neuropathologica communications [Acta Neuropathol Commun] 2025 May 19; Vol. 13 (1), pp. 108. Date of Electronic Publication: 2025 May 19.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960 (Electronic) Linking ISSN: 20515960 NLM ISO Abbreviation: Acta Neuropathol Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2051-5960
DOI:10.1186/s40478-025-02000-4