Identification and validation of poly-metabolite scores for diets high in ultra-processed food: An observational study and post-hoc randomized controlled crossover-feeding trial.

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Title: Identification and validation of poly-metabolite scores for diets high in ultra-processed food: An observational study and post-hoc randomized controlled crossover-feeding trial.
Authors: Abar L; Division of Cancer Epidemiology and Genetics, National Cancer Institute (NCI), Rockville, Maryland, United States of America., Steele EM; Department of Nutrition, School of Public Health, University of Sao Paulo, Sao Paulo, Brazil.; Center for Epidemiological Studies in Health and Nutrition, University of Sao Paulo, Sao Paulo, Brazil., Lee SK; Division of Cancer Epidemiology and Genetics, Biostatistics Branch, NCI, Bethesda, Maryland, United States of America., Kahle L; Information Management Services, Inc. Beltsville, Maryland, United States of America., Moore SC; Division of Cancer Epidemiology and Genetics, National Cancer Institute (NCI), Rockville, Maryland, United States of America., Watts E; Division of Cancer Epidemiology and Genetics, National Cancer Institute (NCI), Rockville, Maryland, United States of America., O'Connell CP; Division of Cancer Epidemiology and Genetics, National Cancer Institute (NCI), Rockville, Maryland, United States of America., Matthews CE; Division of Cancer Epidemiology and Genetics, National Cancer Institute (NCI), Rockville, Maryland, United States of America., Herrick KA; Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Rockville, Maryland, United States of America., Hall KD; Laboratory of Biological Modeling, National Institute of Diabetes and Digestive Kidney Diseases, Bethesda, Maryland, United States of America., O'Connor LE; Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Rockville, Maryland, United States of America., Freedman ND; Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Rockville, Maryland, United States of America., Sinha R; Division of Cancer Epidemiology and Genetics, National Cancer Institute (NCI), Rockville, Maryland, United States of America., Hong HG; Division of Cancer Epidemiology and Genetics, Biostatistics Branch, NCI, Bethesda, Maryland, United States of America., Loftfield E; Division of Cancer Epidemiology and Genetics, National Cancer Institute (NCI), Rockville, Maryland, United States of America.
Source: PLoS medicine [PLoS Med] 2025 May 20; Vol. 22 (5), pp. e1004560. Date of Electronic Publication: 2025 May 20 (Print Publication: 2025).
Publication Type: Journal Article; Randomized Controlled Trial; Observational Study; Validation Study
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101231360 Publication Model: eCollection Cited Medium: Internet ISSN: 1549-1676 (Electronic) Linking ISSN: 15491277 NLM ISO Abbreviation: PLoS Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1549-1676
DOI:10.1371/journal.pmed.1004560