Spatial transcriptomics reveal high T cell and monocyte status as predictive and prognostic markers in pancreatic cancer.

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Title: Spatial transcriptomics reveal high T cell and monocyte status as predictive and prognostic markers in pancreatic cancer.
Authors: Han YB; Department of Pathology and Translational Medicine, Seoul National University Bundang Hospital, 82, Fumi-ro 173 Beon-gil, Bundang-gu, Seongnam, 13620, Gyeonggi, Republic of Korea.; Department of Pathology, Seoul National University College of Medicine, 101, Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea., Lee S; Department of Pathology and Translational Medicine, Seoul National University Bundang Hospital, 82, Fumi-ro 173 Beon-gil, Bundang-gu, Seongnam, 13620, Gyeonggi, Republic of Korea.; Precision Medicine Center, Seoul National University Bundang Hospital, Seongnam, 13620, Republic of Korea., Lee JO; Department of Health Science and Technology, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, 08826, Republic of Korea., Jeong SI; Department of Pathology and Translational Medicine, Seoul National University Bundang Hospital, 82, Fumi-ro 173 Beon-gil, Bundang-gu, Seongnam, 13620, Gyeonggi, Republic of Korea.; Department of Pathology, Seoul National University College of Medicine, 101, Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea., Lee KR; Department of Pathology and Translational Medicine, Seoul National University Bundang Hospital, 82, Fumi-ro 173 Beon-gil, Bundang-gu, Seongnam, 13620, Gyeonggi, Republic of Korea.; Department of Pathology, Seoul National University College of Medicine, 101, Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.; Department of Pathology, Green Cross Laboratories, Yongin, 16924, Republic of Korea., Ahn S; Department of Pathology and Translational Genomics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, 03181, Republic of Korea., Jung K; Department of Internal Medicine, Seoul National University Bundang Hospital, 82, Gumi-ro 173 Beon-gil, Bundang-gu, Seongnam, 13620, Gyeonggi, Republic of Korea.; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea., Lee JC; Department of Internal Medicine, Seoul National University Bundang Hospital, 82, Gumi-ro 173 Beon-gil, Bundang-gu, Seongnam, 13620, Gyeonggi, Republic of Korea.; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea., Yoon YS; Department of Surgery, Seoul National University Bundang Hospital, Seongnam, 13620, Republic of Korea., Hwang JH; Department of Internal Medicine, Seoul National University Bundang Hospital, 82, Gumi-ro 173 Beon-gil, Bundang-gu, Seongnam, 13620, Gyeonggi, Republic of Korea.; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea., Han HS; Department of Surgery, Seoul National University Bundang Hospital, Seongnam, 13620, Republic of Korea., Na HY; Department of Pathology and Translational Medicine, Seoul National University Bundang Hospital, 82, Fumi-ro 173 Beon-gil, Bundang-gu, Seongnam, 13620, Gyeonggi, Republic of Korea. heeyoungna86@gmail.com.; Department of Pathology, Seoul National University College of Medicine, 101, Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea. heeyoungna86@gmail.com., Kim J; Department of Internal Medicine, Seoul National University Bundang Hospital, 82, Gumi-ro 173 Beon-gil, Bundang-gu, Seongnam, 13620, Gyeonggi, Republic of Korea. drjaihwan@snu.ac.kr.; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea. drjaihwan@snu.ac.kr.
Source: Journal of translational medicine [J Transl Med] 2025 May 23; Vol. 23 (1), pp. 576. Date of Electronic Publication: 2025 May 23.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1479-5876
DOI:10.1186/s12967-025-06599-9