Efficacy and safety of epaminurad, a potent hURAT1 inhibitor, in patients with gout: a randomized, placebo-controlled, dose-finding study.

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Title: Efficacy and safety of epaminurad, a potent hURAT1 inhibitor, in patients with gout: a randomized, placebo-controlled, dose-finding study.
Authors: Jun JB; Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea., Lee HS; Division of Rheumatology, Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea., Kim SH; Division of Rheumatology, Department of Internal Medicine, Keimyung University College of Medicine, Daegu, Korea., Lee SG; Division of Rheumatology, Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea., Lim DH; Division of Rheumatology, Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea., Kim J; Division of Rheumatology, Department of Internal Medicine, Chungnam National University College of Medicine, Daejeon, Korea., Park YB; Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea., Lim MJ; Division of Rheumatology, Department of Internal Medicine, Inha University, Incheon, Korea., Hong SJ; Department of Rheumatology, College of Medicine, Kyung Hee University Hospital, Kyung Hee University, Seoul, Korea., Choi HJ; Division of Rheumatology, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Korea., Lee SS; Division of Rheumatology, Department of Internal Medicine, Chonnam National University Medical School & Hospital, Gwangju, Korea., Kim HA; Division of Rheumatology, Department of Internal Medicine, Hallym University Sacred Heart Hospital, Anyang, Korea., Hwang J; Department of Rheumatology, College of Medicine, Kyung Hee University Hospital, Kyung Hee University, Seoul, Korea., Suh CH; Department of Rheumatology, Ajou University School of Medicine, Suwon, Korea., Han S; Division of Rheumatology, Departments of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea., Choe JY; Division of Rheumatology, Department of Internal Medicine, Daegu Catholic University School of Medicine, Daegu, Korea., Yoo WH; Division of Rheumatology, Department of Internal Medicine, Jeonbuk National University Medical School, Jeonju, Korea., Song JS; Division of Rheumatology, Department of Internal Medicine, Chung-Ang University School of Medicine, 102 Heukseok-ro, Dongjak-gu, Seoul, 06973, Korea. drsong@cau.ac.kr.
Source: Arthritis research & therapy [Arthritis Res Ther] 2025 May 26; Vol. 27 (1), pp. 113. Date of Electronic Publication: 2025 May 26.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase II
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101154438 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-6362 (Electronic) Linking ISSN: 14786354 NLM ISO Abbreviation: Arthritis Res Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1478-6362
DOI:10.1186/s13075-025-03577-w