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Efficacy and safety of epaminurad, a potent hURAT1 inhibitor, in patients with gout: a randomized, placebo-controlled, dose-finding study.

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Title: Efficacy and safety of epaminurad, a potent hURAT1 inhibitor, in patients with gout: a randomized, placebo-controlled, dose-finding study.
Authors: Jun JB; Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea., Lee HS; Division of Rheumatology, Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea., Kim SH; Division of Rheumatology, Department of Internal Medicine, Keimyung University College of Medicine, Daegu, Korea., Lee SG; Division of Rheumatology, Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea., Lim DH; Division of Rheumatology, Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea., Kim J; Division of Rheumatology, Department of Internal Medicine, Chungnam National University College of Medicine, Daejeon, Korea., Park YB; Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea., Lim MJ; Division of Rheumatology, Department of Internal Medicine, Inha University, Incheon, Korea., Hong SJ; Department of Rheumatology, College of Medicine, Kyung Hee University Hospital, Kyung Hee University, Seoul, Korea., Choi HJ; Division of Rheumatology, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Korea., Lee SS; Division of Rheumatology, Department of Internal Medicine, Chonnam National University Medical School & Hospital, Gwangju, Korea., Kim HA; Division of Rheumatology, Department of Internal Medicine, Hallym University Sacred Heart Hospital, Anyang, Korea., Hwang J; Department of Rheumatology, College of Medicine, Kyung Hee University Hospital, Kyung Hee University, Seoul, Korea., Suh CH; Department of Rheumatology, Ajou University School of Medicine, Suwon, Korea., Han S; Division of Rheumatology, Departments of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea., Choe JY; Division of Rheumatology, Department of Internal Medicine, Daegu Catholic University School of Medicine, Daegu, Korea., Yoo WH; Division of Rheumatology, Department of Internal Medicine, Jeonbuk National University Medical School, Jeonju, Korea., Song JS; Division of Rheumatology, Department of Internal Medicine, Chung-Ang University School of Medicine, 102 Heukseok-ro, Dongjak-gu, Seoul, 06973, Korea. drsong@cau.ac.kr.
Source: Arthritis research & therapy [Arthritis Res Ther] 2025 May 26; Vol. 27 (1), pp. 113. Date of Electronic Publication: 2025 May 26.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase II
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101154438 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-6362 (Electronic) Linking ISSN: 14786354 NLM ISO Abbreviation: Arthritis Res Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Efficacy and safety of epaminurad, a potent hURAT1 inhibitor, in patients with gout: a randomized, placebo-controlled, dose-finding study.
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  Data: <searchLink fieldCode="AU" term="%22Jun+JB%22">Jun JB</searchLink>; Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Lee+HS%22">Lee HS</searchLink>; Division of Rheumatology, Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+SH%22">Kim SH</searchLink>; Division of Rheumatology, Department of Internal Medicine, Keimyung University College of Medicine, Daegu, Korea.<br /><searchLink fieldCode="AU" term="%22Lee+SG%22">Lee SG</searchLink>; Division of Rheumatology, Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.<br /><searchLink fieldCode="AU" term="%22Lim+DH%22">Lim DH</searchLink>; Division of Rheumatology, Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; Division of Rheumatology, Department of Internal Medicine, Chungnam National University College of Medicine, Daejeon, Korea.<br /><searchLink fieldCode="AU" term="%22Park+YB%22">Park YB</searchLink>; Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Lim+MJ%22">Lim MJ</searchLink>; Division of Rheumatology, Department of Internal Medicine, Inha University, Incheon, Korea.<br /><searchLink fieldCode="AU" term="%22Hong+SJ%22">Hong SJ</searchLink>; Department of Rheumatology, College of Medicine, Kyung Hee University Hospital, Kyung Hee University, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Choi+HJ%22">Choi HJ</searchLink>; Division of Rheumatology, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Korea.<br /><searchLink fieldCode="AU" term="%22Lee+SS%22">Lee SS</searchLink>; Division of Rheumatology, Department of Internal Medicine, Chonnam National University Medical School & Hospital, Gwangju, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+HA%22">Kim HA</searchLink>; Division of Rheumatology, Department of Internal Medicine, Hallym University Sacred Heart Hospital, Anyang, Korea.<br /><searchLink fieldCode="AU" term="%22Hwang+J%22">Hwang J</searchLink>; Department of Rheumatology, College of Medicine, Kyung Hee University Hospital, Kyung Hee University, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Suh+CH%22">Suh CH</searchLink>; Department of Rheumatology, Ajou University School of Medicine, Suwon, Korea.<br /><searchLink fieldCode="AU" term="%22Han+S%22">Han S</searchLink>; Division of Rheumatology, Departments of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea.<br /><searchLink fieldCode="AU" term="%22Choe+JY%22">Choe JY</searchLink>; Division of Rheumatology, Department of Internal Medicine, Daegu Catholic University School of Medicine, Daegu, Korea.<br /><searchLink fieldCode="AU" term="%22Yoo+WH%22">Yoo WH</searchLink>; Division of Rheumatology, Department of Internal Medicine, Jeonbuk National University Medical School, Jeonju, Korea.<br /><searchLink fieldCode="AU" term="%22Song+JS%22">Song JS</searchLink>; Division of Rheumatology, Department of Internal Medicine, Chung-Ang University School of Medicine, 102 Heukseok-ro, Dongjak-gu, Seoul, 06973, Korea. drsong@cau.ac.kr.
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  Data: <searchLink fieldCode="JN" term="%22101154438%22">Arthritis research & therapy</searchLink> [Arthritis Res Ther] 2025 May 26; Vol. 27 (1), pp. 113. <i>Date of Electronic Publication: </i>2025 May 26.
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  Data: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase II
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101154438 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1478-6362 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214786354%22">14786354 </searchLink><i>NLM ISO Abbreviation: </i>Arthritis Res Ther <i>Subsets: </i>MEDLINE
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