Distinct structural deficits in treatment-resistant schizophrenia and their putative neurotransmitter basis: a source-based morphometry analysis.

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Title: Distinct structural deficits in treatment-resistant schizophrenia and their putative neurotransmitter basis: a source-based morphometry analysis.
Authors: Huang H; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China.; Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, QC, Canada., Wang X; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China., Qin X; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China., Xu R; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China., Xiong Y; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China., Chen C; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China., Wan Q; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China., Liu H; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China., Shu C; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China., Yuan W; Department of Psychiatry, Yidu People's Hospital, Yidu, China., Peng Y; Department of Psychiatry, Yidu People's Hospital, Yidu, China., Zhou Y; Institute of Psychology, Chinese Academy of Sciences, Beijing, China., Wang H; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China. hlwang@whu.edu.cn.; Hubei Provincial Key Laboratory of Developmentally Originated Disease, Wuhan, China. hlwang@whu.edu.cn., Palaniyappan L; Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, QC, Canada. lena.palaniyappan@mcgill.ca.; Department of Psychiatry, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada. lena.palaniyappan@mcgill.ca.; Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada. lena.palaniyappan@mcgill.ca.
Source: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology [Neuropsychopharmacology] 2025 Nov; Vol. 50 (12), pp. 1807-1816. Date of Electronic Publication: 2025 May 28.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8904907 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1740-634X (Electronic) Linking ISSN: 0893133X NLM ISO Abbreviation: Neuropsychopharmacology Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1740-634X
DOI:10.1038/s41386-025-02135-x