Mutations that prevent phosphorylation of the BMP4 prodomain impair proteolytic maturation of homodimers leading to lethality in mice.

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Title: Mutations that prevent phosphorylation of the BMP4 prodomain impair proteolytic maturation of homodimers leading to lethality in mice.
Authors: Kim HS; Department of Neurobiology, University of Utah, Salt Lake City, United States., Sanchez ML; Department of Neurobiology, University of Utah, Salt Lake City, United States., Silva J; Department of Neurobiology, University of Utah, Salt Lake City, United States., Schubert HL; Department of Biochemistry, University of Utah, Salt Lake City, United States., Dennis R; Department of Neurobiology, University of Utah, Salt Lake City, United States., Hill CP; Department of Biochemistry, University of Utah, Salt Lake City, United States., Christian JL; Department of Neurobiology, University of Utah, Salt Lake City, United States.; Internal Medicine, Division of Hematology and Hematologic Malignancies, University of Utah, Salt Lake City, United States.
Source: ELife [Elife] 2025 May 29; Vol. 14. Date of Electronic Publication: 2025 May 29.
Publication Type: Journal Article
Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2050-084X
DOI:10.7554/eLife.105018