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Developing Pharmaceutically Relevant Pd-Catalyzed C-N Coupling Reactivity Models Leveraging High-Throughput Experimentation.

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Bibliographic Details
Title: Developing Pharmaceutically Relevant Pd-Catalyzed C-N Coupling Reactivity Models Leveraging High-Throughput Experimentation.
Authors: Ha SK; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States., Kalyani D; Discovery Chemistry, Merck & Co., Inc., Rahway, New Jersey 07065, United States., West MS; Discovery Chemistry, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Xu J; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States., Lam YH; Discovery Chemistry, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Struble T; Discovery Chemistry, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Dreher S; Discovery Chemistry, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Krska SW; Discovery Chemistry, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Buchwald SL; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States., Jensen KF; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.
Source: Journal of the American Chemical Society [J Am Chem Soc] 2025 Jun 11; Vol. 147 (23), pp. 19602-19613. Date of Electronic Publication: 2025 May 29.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1520-5126
DOI:10.1021/jacs.5c00933