Multi-tissue expression and splicing data prioritise anatomical subsite- and sex-specific colorectal cancer susceptibility genes.

Saved in:
Bibliographic Details
Title: Multi-tissue expression and splicing data prioritise anatomical subsite- and sex-specific colorectal cancer susceptibility genes.
Authors: Hazelwood E; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Canson DM; Population Health Program, QIMR Berghofer, Brisbane, QLD, Australia., Deslandes B; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Wang X; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia., Kho PF; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Legge D; Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Constantinescu AE; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Lee MA; Nutrition and Metabolism, International Agency for Research on Cancer, WHO, Lyon, France., Bishop DT; Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK., Chan AT; Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA., Gruber SB; Department of Medical Oncology & Therapeutics Research and Center for Precision Medicine, City of Hope National Medical Center, Duarte, CA, USA., Hampe J; Department of Medicine I, University Hospital Dresden, Technische Universität Dresden (TU Dresden), Dresden, Germany., Le Marchand L; University of Hawaii Cancer Center, Honolulu, HI, USA., Woods MO; Memorial University of Newfoundland, Discipline of Genetics, St. John's, NF, Canada., Pai RK; Department of Pathology and Laboratory Medicine, Mayo Clinic, Arizona, Scottsdale, AZ, USA., Schmit SL; Genomic Medicine Institute, Cleveland Clinic, Cleveland, OH, USA.; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University School of Medicine, Cleveland, OH, USA., Figueiredo JC; Department of Medicine, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center, Nashville, TN, USA., Huyghe JR; Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Murphy N; Nutrition and Metabolism, International Agency for Research on Cancer, WHO, Lyon, France., Gunter MJ; Nutrition and Metabolism, International Agency for Research on Cancer, WHO, Lyon, France.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Richardson TG; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Whitehall VLJ; Conjoint Gastroenterology Laboratory, QIMR Berghofer Medical Research Institute, Herston, QLD, Australia.; Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia.; Conjoint Internal Medicine Laboratory, Pathology Queensland, Queensland Health, Brisbane, QLD, Australia., Vincent EE; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.; Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Glubb DM; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia., O'Mara TA; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia. Tracy.OMara@qimrb.edu.au.; Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia. Tracy.OMara@qimrb.edu.au.
Source: Nature communications [Nat Commun] 2025 May 30; Vol. 16 (1), pp. 5043. Date of Electronic Publication: 2025 May 30.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2041-1723
DOI:10.1038/s41467-025-60275-6