Utilizing metabolism-based structure-activity relationships and biokinetic modeling for toxicological evaluation: A case study on L-menthyl D-Lactate.

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Title: Utilizing metabolism-based structure-activity relationships and biokinetic modeling for toxicological evaluation: A case study on L-menthyl D-Lactate.
Authors: Ellison C; The Procter & Gamble Company, 8700 Mason Montgomery Road, Cincinnati, OH, 45040, USA. Electronic address: ellison.ca@pg.com., Blubaugh J; The Procter & Gamble Company, 8700 Mason Montgomery Road, Cincinnati, OH, 45040, USA., Engled S; The Procter & Gamble Company, 8700 Mason Montgomery Road, Cincinnati, OH, 45040, USA., Karb M; The Procter & Gamble Company, 8700 Mason Montgomery Road, Cincinnati, OH, 45040, USA., Lester C; The Procter & Gamble Company, 8700 Mason Montgomery Road, Cincinnati, OH, 45040, USA., Obringer C; The Procter & Gamble Company, 8700 Mason Montgomery Road, Cincinnati, OH, 45040, USA., Woeller K; The Procter & Gamble Company, 6300 Center Hill Ave, Cincinnati, OH, 45232, USA.
Source: Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2025 Nov; Vol. 162, pp. 105872. Date of Electronic Publication: 2025 May 30.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8214983 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0295 (Electronic) Linking ISSN: 02732300 NLM ISO Abbreviation: Regul Toxicol Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1096-0295
DOI:10.1016/j.yrtph.2025.105872