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Trichomonas vaginalis extracellular vesicles activate the NLRP3 inflammasome and TLR3-mediated inflammatory cascades in host cells.

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Title: Trichomonas vaginalis extracellular vesicles activate the NLRP3 inflammasome and TLR3-mediated inflammatory cascades in host cells.
Authors: Huang CY; Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei city, Taiwan.; Host-Parasite Interactions Laboratory, National Defense Medical Center, Taipei city, Taiwan., Chiu SF; Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei city, Taiwan.; Host-Parasite Interactions Laboratory, National Defense Medical Center, Taipei city, Taiwan.; Department of Inspection, Taipei City Hospital, Taipei City, Taiwan., Chu LJ; Graduate Institute of Biomedical Sciences, Chang Gung University, Taoyuan, Taiwan.; Molecular Medicine Research Center, Chang Gung University, Taoyuan, Taiwan.; Department of Otolaryngology - Head & Neck Surgery, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan., Yeh YM; Genomic Medicine Core Laboratory, Chang Gung Memorial Hospital, Taoyuan, Taiwan., Huang PJ; Genomic Medicine Core Laboratory, Chang Gung Memorial Hospital, Taoyuan, Taiwan.; Department of Biomedical Sciences, Chang Gung University, Taoyuan, Taiwan., Lan KL; Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei city, Taiwan., Tsai YL; Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei city, Taiwan., Liu CC; Host-Parasite Interactions Laboratory, National Defense Medical Center, Taipei city, Taiwan.; Graduate Institute of Pathology and Parasitology, National Defense Medical Center, Taipei City, Taiwan., Chen CF; Graduate Institute of Life Sciences, National Defense Medical Center, Taipei city, Taiwan., Lin WN; Graduate Institute of Biomedical and Pharmaceutical Science, Fu Jen Catholic University, New Taipei City, Taiwan., Huang KY; Host-Parasite Interactions Laboratory, National Defense Medical Center, Taipei city, Taiwan.; Graduate Institute of Pathology and Parasitology, National Defense Medical Center, Taipei City, Taiwan.
Source: PLoS pathogens [PLoS Pathog] 2025 Jun 02; Vol. 21 (6), pp. e1013216. Date of Electronic Publication: 2025 Jun 02 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Trichomonas vaginalis extracellular vesicles activate the NLRP3 inflammasome and TLR3-mediated inflammatory cascades in host cells.
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  Data: <searchLink fieldCode="AU" term="%22Huang+CY%22">Huang CY</searchLink>; Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei city, Taiwan.; Host-Parasite Interactions Laboratory, National Defense Medical Center, Taipei city, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chiu+SF%22">Chiu SF</searchLink>; Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei city, Taiwan.; Host-Parasite Interactions Laboratory, National Defense Medical Center, Taipei city, Taiwan.; Department of Inspection, Taipei City Hospital, Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chu+LJ%22">Chu LJ</searchLink>; Graduate Institute of Biomedical Sciences, Chang Gung University, Taoyuan, Taiwan.; Molecular Medicine Research Center, Chang Gung University, Taoyuan, Taiwan.; Department of Otolaryngology - Head & Neck Surgery, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yeh+YM%22">Yeh YM</searchLink>; Genomic Medicine Core Laboratory, Chang Gung Memorial Hospital, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+PJ%22">Huang PJ</searchLink>; Genomic Medicine Core Laboratory, Chang Gung Memorial Hospital, Taoyuan, Taiwan.; Department of Biomedical Sciences, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lan+KL%22">Lan KL</searchLink>; Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei city, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+YL%22">Tsai YL</searchLink>; Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei city, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liu+CC%22">Liu CC</searchLink>; Host-Parasite Interactions Laboratory, National Defense Medical Center, Taipei city, Taiwan.; Graduate Institute of Pathology and Parasitology, National Defense Medical Center, Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+CF%22">Chen CF</searchLink>; Graduate Institute of Life Sciences, National Defense Medical Center, Taipei city, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+WN%22">Lin WN</searchLink>; Graduate Institute of Biomedical and Pharmaceutical Science, Fu Jen Catholic University, New Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+KY%22">Huang KY</searchLink>; Host-Parasite Interactions Laboratory, National Defense Medical Center, Taipei city, Taiwan.; Graduate Institute of Pathology and Parasitology, National Defense Medical Center, Taipei City, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22101238921%22">PLoS pathogens</searchLink> [PLoS Pathog] 2025 Jun 02; Vol. 21 (6), pp. e1013216. <i>Date of Electronic Publication: </i>2025 Jun 02 (<i>Print Publication: </i>2025).
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              Text: 2025 Jun 02
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