ELF1-mediated transactivation of METTL3/YTHDF2 promotes nucleus pulposus cell senescence via m6A-dependent destabilization of E2F3 mRNA in intervertebral disc degeneration.
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| Title: | ELF1-mediated transactivation of METTL3/YTHDF2 promotes nucleus pulposus cell senescence via m6A-dependent destabilization of E2F3 mRNA in intervertebral disc degeneration. |
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| Authors: | Liu XW; Department of Spinal Surgery, Shanghai East Hospital, School of Medicine, Tongji University, 200092, Shanghai, China., Xu HW; Department of Spinal Surgery, Shanghai East Hospital, School of Medicine, Tongji University, 200092, Shanghai, China., Zhang SB; Department of Spinal Surgery, Shanghai East Hospital, School of Medicine, Tongji University, 200092, Shanghai, China., Yi YY; Department of Spinal Surgery, Shanghai East Hospital, School of Medicine, Tongji University, 200092, Shanghai, China., Chang SJ; Department of Spinal Surgery, Shanghai East Hospital, School of Medicine, Tongji University, 200092, Shanghai, China., Wang SJ; Department of Spinal Surgery, Shanghai East Hospital, School of Medicine, Tongji University, 200092, Shanghai, China. kingspine@163.com. |
| Source: | Cell death discovery [Cell Death Discov] 2025 Jun 04; Vol. 11 (1), pp. 267. Date of Electronic Publication: 2025 Jun 04. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2058-7716 |
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| DOI: | 10.1038/s41420-025-02515-8 |
