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4'-C-Cholesterol/Pyridyl-2'-O-Methyl Uridine-Functionalized siRNA Enhances Stability and Carrier-Free Gene Silencing.

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Title: 4'-C-Cholesterol/Pyridyl-2'-O-Methyl Uridine-Functionalized siRNA Enhances Stability and Carrier-Free Gene Silencing.
Authors: Sar S; Department of Chemistry, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal 721302, India., Gupta S; School of Applied and Interdisciplinary Sciences, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700032, India., Das G; Department of Chemistry, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal 721302, India., Sharma SN; School of Applied and Interdisciplinary Sciences, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700032, India., K D; School of Applied and Interdisciplinary Sciences, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700032, India.; School of Medical Science and Technology, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal 721302, India., Ghosh A; School of Applied and Interdisciplinary Sciences, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700032, India., Bagale SS; Department of Chemistry, Indian Institute of Technology Bombay, Mumbai 400076, India., Gangopadhyay S; Department of Chemistry, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal 721302, India., Sinha S; School of Applied and Interdisciplinary Sciences, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700032, India., Gore KR; Department of Chemistry, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal 721302, India.
Source: Bioconjugate chemistry [Bioconjug Chem] 2025 Jun 18; Vol. 36 (6), pp. 1234-1246. Date of Electronic Publication: 2025 Jun 05.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9010319 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4812 (Electronic) Linking ISSN: 10431802 NLM ISO Abbreviation: Bioconjug Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1520-4812
DOI:10.1021/acs.bioconjchem.5c00079