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Protective effects of licofelone on experimental skin flap survival rat model via cyclooxygenase and lipoxygenase inhibition: involvement of inflammatory cytokines and nitric oxide.

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Title: Protective effects of licofelone on experimental skin flap survival rat model via cyclooxygenase and lipoxygenase inhibition: involvement of inflammatory cytokines and nitric oxide.
Authors: Masoumi M; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, 13145-784, Iran.; Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran., Ahmadi S; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, 13145-784, Iran.; Department of Biotechnology, University of Science and Culture (USC), Tehran, Iran., Mohammad Jafari R; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, 13145-784, Iran. rmjafari@sina.tums.ac.ir.; Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. rmjafari@sina.tums.ac.ir., Manavi MA; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, 13145-784, Iran.; Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran., Tavangar SM; Department of Pathology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, 1416753955, Iran., Dehpour AR; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, 13145-784, Iran. dehpour@yahoo.com.; Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. dehpour@yahoo.com.
Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2025 Dec; Vol. 398 (12), pp. 17187-17199. Date of Electronic Publication: 2025 Jun 06.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1432-1912
DOI:10.1007/s00210-025-04304-7