Examining the viability of modern endoscopic endonasal surgery as a first-line treatment for macroprolactinomas: a multicentric study on the results and significance of the highest preoperative prolactin level in predicting long-term surgical outcomes.

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Title: Examining the viability of modern endoscopic endonasal surgery as a first-line treatment for macroprolactinomas: a multicentric study on the results and significance of the highest preoperative prolactin level in predicting long-term surgical outcomes.
Authors: Khaleghi M; 1Department of Neurosurgery, Wexner Medical Center, The Ohio State University, Columbus, Ohio., Huntoon KM; 1Department of Neurosurgery, Wexner Medical Center, The Ohio State University, Columbus, Ohio., Zandbergen IM; 2Department of Neurosurgery, Center for Endocrine Tumours Leiden, Leiden University Medical Center, Leiden, The Netherlands.; 3Department of Medicine, Division of Endocrinology, Center for Endocrine Tumours Leiden, Leiden University Medical Center, Leiden, The Netherlands., White TG; 4Department of Neurosurgery, Hofstra University Northwell Health, Manhasset, New York; and., Bakker LEH; 3Department of Medicine, Division of Endocrinology, Center for Endocrine Tumours Leiden, Leiden University Medical Center, Leiden, The Netherlands., Verstegen MJT; 2Department of Neurosurgery, Center for Endocrine Tumours Leiden, Leiden University Medical Center, Leiden, The Netherlands., Ghalib LM; 5Department of Endocrinology, Wexner Medical Center, The Ohio State University, Columbus, Ohio., Pelsma ICM; 3Department of Medicine, Division of Endocrinology, Center for Endocrine Tumours Leiden, Leiden University Medical Center, Leiden, The Netherlands., Golub D; 4Department of Neurosurgery, Hofstra University Northwell Health, Manhasset, New York; and., Kuffer A; 4Department of Neurosurgery, Hofstra University Northwell Health, Manhasset, New York; and., Dehdashti AR; 4Department of Neurosurgery, Hofstra University Northwell Health, Manhasset, New York; and., Biermasz NR; 3Department of Medicine, Division of Endocrinology, Center for Endocrine Tumours Leiden, Leiden University Medical Center, Leiden, The Netherlands., Prevedello DM; 1Department of Neurosurgery, Wexner Medical Center, The Ohio State University, Columbus, Ohio.
Source: Journal of neurosurgery [J Neurosurg] 2025 Jun 06; Vol. 143 (5), pp. 1364-1376. Date of Electronic Publication: 2025 Jun 06 (Print Publication: 2025).
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: American Association of Neurological Surgeons Country of Publication: United States NLM ID: 0253357 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1933-0693 (Electronic) Linking ISSN: 00223085 NLM ISO Abbreviation: J Neurosurg Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1933-0693
DOI:10.3171/2025.1.JNS241645