Developing an in vitro osteochondral micro-physiological system for modeling cartilage-bone crosstalk in arthritis.

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Title: Developing an in vitro osteochondral micro-physiological system for modeling cartilage-bone crosstalk in arthritis.
Authors: Smith KWY; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, United States.; Pulmonary and Sleep Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, United States., Fung SL; Pulmonary and Sleep Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, United States., Wu HF; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, United States.; Pulmonary and Sleep Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, United States., Chiesa I; Pulmonary and Sleep Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, United States.; Department of Information Engineering and Research Center E. Piaggio, University of Pisa, Pisa, Italy., Vozzi G; Department of Information Engineering and Research Center E. Piaggio, University of Pisa, Pisa, Italy., De Maria C; Department of Information Engineering and Research Center E. Piaggio, University of Pisa, Pisa, Italy., Gottardi R; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, United States.; Pulmonary and Sleep Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, United States.; Division of Otolaryngology, Department of Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, United States.; Department of Otorhinolaryngology, Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.; Department of Orthopaedic Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States.; Ri.MED Foundation, Palermo, PA, Italy.
Source: Frontiers in immunology [Front Immunol] 2025 May 26; Vol. 16, pp. 1495613. Date of Electronic Publication: 2025 May 26 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2025.1495613