Novel dual-lumen microneedle delivers adeno-associated viral vectors in the guinea pig inner ear via the round window membrane.
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| Title: | Novel dual-lumen microneedle delivers adeno-associated viral vectors in the guinea pig inner ear via the round window membrane. |
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| Authors: | Hammer DR; Department of Mechanical Engineering, Columbia University, New York, NY, 10027, USA., Voruz F; Department of Mechanical Engineering, Columbia University, New York, NY, 10027, USA.; Department of Otolaryngology-Head and Neck Surgery, New York-Presbyterian/Columbia University Irving Medical Center, New York City, NY, 10032, USA., Aksit A; Department of Mechanical Engineering, Columbia University, New York, NY, 10027, USA., Breil E; Department of Mechanical Engineering, Columbia University, New York, NY, 10027, USA.; Department of Otolaryngology-Head and Neck Surgery, New York-Presbyterian/Columbia University Irving Medical Center, New York City, NY, 10032, USA., Rousset F; The Inner Ear and Olfaction Lab, Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland., Senn P; The Inner Ear and Olfaction Lab, Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Otorhinolaryngology-Head and Neck Surgery, Department of Clinical Neurosciences, University Hospital of Geneva, Geneva, Switzerland., Ilmjärv S; Antion Biosciences SA, Plan-les-Ouates, Switzerland., Olson ES; Department of Otolaryngology-Head and Neck Surgery, New York-Presbyterian/Columbia University Irving Medical Center, New York City, NY, 10032, USA.; Department of Biomedical Engineering, Columbia University, New York, NY, 10027, USA., Lalwani AK; Department of Mechanical Engineering, Columbia University, New York, NY, 10027, USA. akl2144@cumc.columbia.edu.; Department of Otolaryngology-Head and Neck Surgery, New York-Presbyterian/Columbia University Irving Medical Center, New York City, NY, 10032, USA. akl2144@cumc.columbia.edu., Kysar JW; Department of Mechanical Engineering, Columbia University, New York, NY, 10027, USA. jk2079@columbia.edu.; Department of Otolaryngology-Head and Neck Surgery, New York-Presbyterian/Columbia University Irving Medical Center, New York City, NY, 10032, USA. jk2079@columbia.edu. |
| Source: | Biomedical microdevices [Biomed Microdevices] 2025 Jun 10; Vol. 27 (2), pp. 27. Date of Electronic Publication: 2025 Jun 10. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer US Country of Publication: United States NLM ID: 100887374 Publication Model: Electronic Cited Medium: Internet ISSN: 1572-8781 (Electronic) Linking ISSN: 13872176 NLM ISO Abbreviation: Biomed Microdevices Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1572-8781 |
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| DOI: | 10.1007/s10544-025-00751-4 |
