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Novel dual-lumen microneedle delivers adeno-associated viral vectors in the guinea pig inner ear via the round window membrane.

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Title: Novel dual-lumen microneedle delivers adeno-associated viral vectors in the guinea pig inner ear via the round window membrane.
Authors: Hammer DR; Department of Mechanical Engineering, Columbia University, New York, NY, 10027, USA., Voruz F; Department of Mechanical Engineering, Columbia University, New York, NY, 10027, USA.; Department of Otolaryngology-Head and Neck Surgery, New York-Presbyterian/Columbia University Irving Medical Center, New York City, NY, 10032, USA., Aksit A; Department of Mechanical Engineering, Columbia University, New York, NY, 10027, USA., Breil E; Department of Mechanical Engineering, Columbia University, New York, NY, 10027, USA.; Department of Otolaryngology-Head and Neck Surgery, New York-Presbyterian/Columbia University Irving Medical Center, New York City, NY, 10032, USA., Rousset F; The Inner Ear and Olfaction Lab, Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland., Senn P; The Inner Ear and Olfaction Lab, Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Otorhinolaryngology-Head and Neck Surgery, Department of Clinical Neurosciences, University Hospital of Geneva, Geneva, Switzerland., Ilmjärv S; Antion Biosciences SA, Plan-les-Ouates, Switzerland., Olson ES; Department of Otolaryngology-Head and Neck Surgery, New York-Presbyterian/Columbia University Irving Medical Center, New York City, NY, 10032, USA.; Department of Biomedical Engineering, Columbia University, New York, NY, 10027, USA., Lalwani AK; Department of Mechanical Engineering, Columbia University, New York, NY, 10027, USA. akl2144@cumc.columbia.edu.; Department of Otolaryngology-Head and Neck Surgery, New York-Presbyterian/Columbia University Irving Medical Center, New York City, NY, 10032, USA. akl2144@cumc.columbia.edu., Kysar JW; Department of Mechanical Engineering, Columbia University, New York, NY, 10027, USA. jk2079@columbia.edu.; Department of Otolaryngology-Head and Neck Surgery, New York-Presbyterian/Columbia University Irving Medical Center, New York City, NY, 10032, USA. jk2079@columbia.edu.
Source: Biomedical microdevices [Biomed Microdevices] 2025 Jun 10; Vol. 27 (2), pp. 27. Date of Electronic Publication: 2025 Jun 10.
Publication Type: Journal Article
Journal Info: Publisher: Springer US Country of Publication: United States NLM ID: 100887374 Publication Model: Electronic Cited Medium: Internet ISSN: 1572-8781 (Electronic) Linking ISSN: 13872176 NLM ISO Abbreviation: Biomed Microdevices Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Novel dual-lumen microneedle delivers adeno-associated viral vectors in the guinea pig inner ear via the round window membrane.
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  Data: <searchLink fieldCode="AU" term="%22Hammer+DR%22">Hammer DR</searchLink>; Department of Mechanical Engineering, Columbia University, New York, NY, 10027, USA.<br /><searchLink fieldCode="AU" term="%22Voruz+F%22">Voruz F</searchLink>; Department of Mechanical Engineering, Columbia University, New York, NY, 10027, USA.; Department of Otolaryngology-Head and Neck Surgery, New York-Presbyterian/Columbia University Irving Medical Center, New York City, NY, 10032, USA.<br /><searchLink fieldCode="AU" term="%22Aksit+A%22">Aksit A</searchLink>; Department of Mechanical Engineering, Columbia University, New York, NY, 10027, USA.<br /><searchLink fieldCode="AU" term="%22Breil+E%22">Breil E</searchLink>; Department of Mechanical Engineering, Columbia University, New York, NY, 10027, USA.; Department of Otolaryngology-Head and Neck Surgery, New York-Presbyterian/Columbia University Irving Medical Center, New York City, NY, 10032, USA.<br /><searchLink fieldCode="AU" term="%22Rousset+F%22">Rousset F</searchLink>; The Inner Ear and Olfaction Lab, Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Senn+P%22">Senn P</searchLink>; The Inner Ear and Olfaction Lab, Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Otorhinolaryngology-Head and Neck Surgery, Department of Clinical Neurosciences, University Hospital of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ilmjärv+S%22">Ilmjärv S</searchLink>; Antion Biosciences SA, Plan-les-Ouates, Switzerland.<br /><searchLink fieldCode="AU" term="%22Olson+ES%22">Olson ES</searchLink>; Department of Otolaryngology-Head and Neck Surgery, New York-Presbyterian/Columbia University Irving Medical Center, New York City, NY, 10032, USA.; Department of Biomedical Engineering, Columbia University, New York, NY, 10027, USA.<br /><searchLink fieldCode="AU" term="%22Lalwani+AK%22">Lalwani AK</searchLink>; Department of Mechanical Engineering, Columbia University, New York, NY, 10027, USA. akl2144@cumc.columbia.edu.; Department of Otolaryngology-Head and Neck Surgery, New York-Presbyterian/Columbia University Irving Medical Center, New York City, NY, 10032, USA. akl2144@cumc.columbia.edu.<br /><searchLink fieldCode="AU" term="%22Kysar+JW%22">Kysar JW</searchLink>; Department of Mechanical Engineering, Columbia University, New York, NY, 10027, USA. jk2079@columbia.edu.; Department of Otolaryngology-Head and Neck Surgery, New York-Presbyterian/Columbia University Irving Medical Center, New York City, NY, 10032, USA. jk2079@columbia.edu.
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  Data: <searchLink fieldCode="JN" term="%22100887374%22">Biomedical microdevices</searchLink> [Biomed Microdevices] 2025 Jun 10; Vol. 27 (2), pp. 27. <i>Date of Electronic Publication: </i>2025 Jun 10.
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