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The macrophage-intrinsic MDA5/IRF5 axis drives HIV-1 intron-containing RNA-induced inflammatory responses.

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Bibliographic Details
Title: The macrophage-intrinsic MDA5/IRF5 axis drives HIV-1 intron-containing RNA-induced inflammatory responses.
Authors: Ramaswamy S; Department of Virology, Immunology & Microbiology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Akiyama H; Department of Virology, Immunology & Microbiology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Berrigan J; Department of Virology, Immunology & Microbiology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Quiñones-Molina AA; Department of Virology, Immunology & Microbiology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Olson AJ; Section of Infectious Diseases, Department of Medicine, Boston Medical Center, Boston, Massachusetts, USA., Chen Y; Section of Infectious Diseases, Department of Medicine, Boston Medical Center, Boston, Massachusetts, USA., Liang Y; Section of Infectious Diseases, Department of Medicine, Boston Medical Center, Boston, Massachusetts, USA., Henderson AJ; Department of Virology, Immunology & Microbiology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.; Section of Infectious Diseases, Department of Medicine, Boston Medical Center, Boston, Massachusetts, USA., Asundi A; Section of Infectious Diseases, Department of Medicine, Boston Medical Center, Boston, Massachusetts, USA., Sagar M; Department of Virology, Immunology & Microbiology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.; Section of Infectious Diseases, Department of Medicine, Boston Medical Center, Boston, Massachusetts, USA., Gummuluru S; Department of Virology, Immunology & Microbiology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.
Source: The Journal of clinical investigation [J Clin Invest] 2025 Jun 10; Vol. 135 (16). Date of Electronic Publication: 2025 Jun 10 (Print Publication: 2025).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: eCollection Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1558-8238
DOI:10.1172/JCI187663