Hydroxysafflor Yellow A Ameliorates Ischemic Stroke by Inhibiting NLRP3, AIM2, and Pyrin Inflammasome-Mediated Pyroptosis.
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| Title: | Hydroxysafflor Yellow A Ameliorates Ischemic Stroke by Inhibiting NLRP3, AIM2, and Pyrin Inflammasome-Mediated Pyroptosis. |
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| Authors: | Ding YL; State Key Laboratory of Traditional Chinese Medicine Syndrome, The Second Affiliated Hospital of Guangzhou, University of Chinese Medicine, Guangzhou, 510405, China.; Department of Neurology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.; Department of Neurology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510405, China.; Guangdong Provincial Key Laboratory of Research on Emergency in TCM, Guangzhou, 510000, China., Qiao LJ; State Key Laboratory of Traditional Chinese Medicine Syndrome, The Second Affiliated Hospital of Guangzhou, University of Chinese Medicine, Guangzhou, 510405, China.; Department of Neurology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.; Department of Neurology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510405, China.; Guangdong Provincial Key Laboratory of Research on Emergency in TCM, Guangzhou, 510000, China., Fang H; State Key Laboratory of Traditional Chinese Medicine Syndrome, The Second Affiliated Hospital of Guangzhou, University of Chinese Medicine, Guangzhou, 510405, China.; Department of Neurology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.; Department of Neurology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510405, China.; Guangdong Provincial Key Laboratory of Research on Emergency in TCM, Guangzhou, 510000, China., Fan LL; State Key Laboratory of Traditional Chinese Medicine Syndrome, The Second Affiliated Hospital of Guangzhou, University of Chinese Medicine, Guangzhou, 510405, China.; Department of Neurology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.; Department of Neurology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510405, China.; Guangdong Provincial Key Laboratory of Research on Emergency in TCM, Guangzhou, 510000, China., Wu D; State Key Laboratory of Traditional Chinese Medicine Syndrome, The Second Affiliated Hospital of Guangzhou, University of Chinese Medicine, Guangzhou, 510405, China.; Department of Neurology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.; Department of Neurology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510405, China.; Guangdong Provincial Key Laboratory of Research on Emergency in TCM, Guangzhou, 510000, China., Xu JP; State Key Laboratory of Traditional Chinese Medicine Syndrome, The Second Affiliated Hospital of Guangzhou, University of Chinese Medicine, Guangzhou, 510405, China.; Department of Neurology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.; Department of Neurology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510405, China.; Guangdong Provincial Key Laboratory of Research on Emergency in TCM, Guangzhou, 510000, China., Lv QH; State Key Laboratory of Traditional Chinese Medicine Syndrome, The Second Affiliated Hospital of Guangzhou, University of Chinese Medicine, Guangzhou, 510405, China.; Department of Neurology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.; Department of Neurology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510405, China.; Guangdong Provincial Key Laboratory of Research on Emergency in TCM, Guangzhou, 510000, China., Deng MZ; State Key Laboratory of Traditional Chinese Medicine Syndrome, The Second Affiliated Hospital of Guangzhou, University of Chinese Medicine, Guangzhou, 510405, China.; Department of Neurology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.; Department of Neurology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510405, China.; Guangdong Provincial Key Laboratory of Research on Emergency in TCM, Guangzhou, 510000, China., Qiu YH; State Key Laboratory of Traditional Chinese Medicine Syndrome, The Second Affiliated Hospital of Guangzhou, University of Chinese Medicine, Guangzhou, 510405, China.; Department of Neurology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.; Department of Neurology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510405, China.; Guangdong Provincial Key Laboratory of Research on Emergency in TCM, Guangzhou, 510000, China., Zhou ZY; State Key Laboratory of Traditional Chinese Medicine Syndrome, The Second Affiliated Hospital of Guangzhou, University of Chinese Medicine, Guangzhou, 510405, China.; Department of Neurology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.; Department of Neurology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510405, China.; Guangdong Provincial Key Laboratory of Research on Emergency in TCM, Guangzhou, 510000, China., Huang Y; State Key Laboratory of Traditional Chinese Medicine Syndrome, The Second Affiliated Hospital of Guangzhou, University of Chinese Medicine, Guangzhou, 510405, China.; Department of Neurology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.; Department of Neurology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510405, China.; Guangdong Provincial Key Laboratory of Research on Emergency in TCM, Guangzhou, 510000, China., Zheng JY; State Key Laboratory of Traditional Chinese Medicine Syndrome, The Second Affiliated Hospital of Guangzhou, University of Chinese Medicine, Guangzhou, 510405, China. zhengjiayi@gzucm.edu.cn.; Department of Neurology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China. zhengjiayi@gzucm.edu.cn.; Department of Neurology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510405, China. zhengjiayi@gzucm.edu.cn.; Guangdong Provincial Key Laboratory of Research on Emergency in TCM, Guangzhou, 510000, China. zhengjiayi@gzucm.edu.cn., Zhang SJ; State Key Laboratory of Traditional Chinese Medicine Syndrome, The Second Affiliated Hospital of Guangzhou, University of Chinese Medicine, Guangzhou, 510405, China. shijiezhang@gzucm.edu.cn.; Department of Neurology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China. shijiezhang@gzucm.edu.cn.; Department of Neurology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510405, China. shijiezhang@gzucm.edu.cn.; Guangdong Provincial Key Laboratory of Research on Emergency in TCM, Guangzhou, 510000, China. shijiezhang@gzucm.edu.cn., Cai YF; State Key Laboratory of Traditional Chinese Medicine Syndrome, The Second Affiliated Hospital of Guangzhou, University of Chinese Medicine, Guangzhou, 510405, China. caiyefeng@126.com.; Department of Neurology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China. caiyefeng@126.com.; Department of Neurology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510405, China. caiyefeng@126.com.; Guangdong Provincial Key Laboratory of Research on Emergency in TCM, Guangzhou, 510000, China. caiyefeng@126.com. |
| Source: | Neurochemical research [Neurochem Res] 2025 Jun 13; Vol. 50 (3), pp. 201. Date of Electronic Publication: 2025 Jun 13. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 7613461 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-6903 (Electronic) Linking ISSN: 03643190 NLM ISO Abbreviation: Neurochem Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1573-6903 |
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| DOI: | 10.1007/s11064-025-04452-5 |
