Resolving spatial subclonal genomic heterogeneity of loss of heterozygosity and extrachromosomal DNA in gliomas.

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Title: Resolving spatial subclonal genomic heterogeneity of loss of heterozygosity and extrachromosomal DNA in gliomas.
Authors: Webb MG; Department of Translational Genomics, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Chow F; Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., McCullough CG; Department of Translational Genomics, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Zhang B; Department of Translational Genomics, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Lee JJY; Department of Integrative Translational Sciences, City of Hope, Duarte, CA, USA., Bassiouni R; Department of Translational Genomics, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Garrett NE 3rd; Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Hurth K; Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Carpten JD; Department of Translational Genomics, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.; Department of Integrative Translational Sciences, City of Hope, Duarte, CA, USA., Zada G; Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. Gabriel.Zada@med.usc.edu., Craig DW; Department of Translational Genomics, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. dacraig@coh.org.; Department of Integrative Translational Sciences, City of Hope, Duarte, CA, USA. dacraig@coh.org.
Source: Nature communications [Nat Commun] 2025 Jun 13; Vol. 16 (1), pp. 5290. Date of Electronic Publication: 2025 Jun 13.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-59805-z