Comprehensive transcriptome assessment in PBMCs of post-COVID patients at a median follow-up of 28 months after a mild COVID infection reveals upregulation of JAK/STAT signaling and a prolonged immune response.
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| Title: | Comprehensive transcriptome assessment in PBMCs of post-COVID patients at a median follow-up of 28 months after a mild COVID infection reveals upregulation of JAK/STAT signaling and a prolonged immune response. |
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| Authors: | Fineschi S; Department of Public Health and Caring Sciences, Faculty of Medicine, Uppsala University, Uppsala, Sweden.; Östhammar Health Care Centre, Östhammar, Sweden., Klar J; Science for Life Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Lopez Egido JR; Östhammar Health Care Centre, Östhammar, Sweden., Schuster J; Science for Life Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Bergquist J; Analytical Chemistry and Neurochemistry, Department of Chemistry, Biomedicinskt Centrum (BMC), Uppsala University, Uppsala, Sweden.; The ME/CFS Collaborative Research Centre, Uppsala University, Uppsala, Sweden., Kaden R; Department of Medical Sciences, Uppsala University, Akademiska Sjukhuset, Uppsala, Sweden.; Clinical Genomics Uppsala, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Dahl N; Science for Life Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden. |
| Source: | Frontiers in immunology [Front Immunol] 2025 May 30; Vol. 16, pp. 1589589. Date of Electronic Publication: 2025 May 30 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1664-3224 |
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| DOI: | 10.3389/fimmu.2025.1589589 |