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PHD3-VHL axis controls HIV-2 infection through oxygen-dependent hydroxylation and degradation of Vpx.

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Title: PHD3-VHL axis controls HIV-2 infection through oxygen-dependent hydroxylation and degradation of Vpx.
Authors: Miyakawa K; AIDS Research Center, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan.; Influenza Research Center, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan.; Department of Microbiology, Yokohama City University School of Medicine, Yokohama, Japan., Tanaka K; Department of Microbiology, Yokohama City University School of Medicine, Yokohama, Japan., Ino Y; Advanced Medical Research Center, Yokohama City University, Yokohama, Japan., Kimura Y; Advanced Medical Research Center, Yokohama City University, Yokohama, Japan., Kameya T; Department of Bioinformatics and Integrative Omics, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan.; Life Science Laboratory, Technology and Development Division, Kanto Chemical Co., Inc., Isehara, Japan., Mizukoshi F; Department of Bioinformatics and Integrative Omics, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan., Nishi M; Department of Microbiology, Yokohama City University School of Medicine, Yokohama, Japan.; Department of Bioinformatics and Integrative Omics, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan., Yokoyama M; Department of Bioinformatics and Integrative Omics, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan., Nakabayashi J; Institute of Liberal Arts, Institute of Science Tokyo, Ichikawa, Japan., Nomaguchi M; Department of Microbiology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan., Sato H; Department of Bioinformatics and Integrative Omics, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan., Kimura H; Department of Health Science, Graduate School of Health Sciences, Gunma Paz University, Takasaki, Japan., Akari H; Center for the Evolutionary Origins of Human Behavior, Kyoto University, Inuyama, Japan., Miura T; Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan., Takaoka A; Division of Signaling in Cancer and Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan., Hasegawa H; Influenza Research Center, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan.; Institute for Vaccine Research and Development, Hokkaido University, Sapporo, Japan., Matano T; AIDS Research Center, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan.; Institute of Medical Science, University of Tokyo, Tokyo, Japan., Minamishima YA; Department of Biochemistry, Gunma University Graduate School of Medicine, Maebashi, Japan., Ryo A; Department of Microbiology, Yokohama City University School of Medicine, Yokohama, Japan.; Department of Bioinformatics and Integrative Omics, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan.
Source: PLoS pathogens [PLoS Pathog] 2025 Jun 16; Vol. 21 (6), pp. e1013241. Date of Electronic Publication: 2025 Jun 16 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: PHD3-VHL axis controls HIV-2 infection through oxygen-dependent hydroxylation and degradation of Vpx.
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  Data: <searchLink fieldCode="AU" term="%22Miyakawa+K%22">Miyakawa K</searchLink>; AIDS Research Center, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan.; Influenza Research Center, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan.; Department of Microbiology, Yokohama City University School of Medicine, Yokohama, Japan.<br /><searchLink fieldCode="AU" term="%22Tanaka+K%22">Tanaka K</searchLink>; Department of Microbiology, Yokohama City University School of Medicine, Yokohama, Japan.<br /><searchLink fieldCode="AU" term="%22Ino+Y%22">Ino Y</searchLink>; Advanced Medical Research Center, Yokohama City University, Yokohama, Japan.<br /><searchLink fieldCode="AU" term="%22Kimura+Y%22">Kimura Y</searchLink>; Advanced Medical Research Center, Yokohama City University, Yokohama, Japan.<br /><searchLink fieldCode="AU" term="%22Kameya+T%22">Kameya T</searchLink>; Department of Bioinformatics and Integrative Omics, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan.; Life Science Laboratory, Technology and Development Division, Kanto Chemical Co., Inc., Isehara, Japan.<br /><searchLink fieldCode="AU" term="%22Mizukoshi+F%22">Mizukoshi F</searchLink>; Department of Bioinformatics and Integrative Omics, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Nishi+M%22">Nishi M</searchLink>; Department of Microbiology, Yokohama City University School of Medicine, Yokohama, Japan.; Department of Bioinformatics and Integrative Omics, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Yokoyama+M%22">Yokoyama M</searchLink>; Department of Bioinformatics and Integrative Omics, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Nakabayashi+J%22">Nakabayashi J</searchLink>; Institute of Liberal Arts, Institute of Science Tokyo, Ichikawa, Japan.<br /><searchLink fieldCode="AU" term="%22Nomaguchi+M%22">Nomaguchi M</searchLink>; Department of Microbiology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.<br /><searchLink fieldCode="AU" term="%22Sato+H%22">Sato H</searchLink>; Department of Bioinformatics and Integrative Omics, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kimura+H%22">Kimura H</searchLink>; Department of Health Science, Graduate School of Health Sciences, Gunma Paz University, Takasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Akari+H%22">Akari H</searchLink>; Center for the Evolutionary Origins of Human Behavior, Kyoto University, Inuyama, Japan.<br /><searchLink fieldCode="AU" term="%22Miura+T%22">Miura T</searchLink>; Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Takaoka+A%22">Takaoka A</searchLink>; Division of Signaling in Cancer and Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Hasegawa+H%22">Hasegawa H</searchLink>; Influenza Research Center, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan.; Institute for Vaccine Research and Development, Hokkaido University, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Matano+T%22">Matano T</searchLink>; AIDS Research Center, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan.; Institute of Medical Science, University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Minamishima+YA%22">Minamishima YA</searchLink>; Department of Biochemistry, Gunma University Graduate School of Medicine, Maebashi, Japan.<br /><searchLink fieldCode="AU" term="%22Ryo+A%22">Ryo A</searchLink>; Department of Microbiology, Yokohama City University School of Medicine, Yokohama, Japan.; Department of Bioinformatics and Integrative Omics, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101238921%22">PLoS pathogens</searchLink> [PLoS Pathog] 2025 Jun 16; Vol. 21 (6), pp. e1013241. <i>Date of Electronic Publication: </i>2025 Jun 16 (<i>Print Publication: </i>2025).
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