An old spice with new tricks: Curcumin targets adenoma and colorectal cancer stem-like cells associated with poor survival outcomes.

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Title: An old spice with new tricks: Curcumin targets adenoma and colorectal cancer stem-like cells associated with poor survival outcomes.
Authors: Khan S; Leicester Cancer Research Centre, University of Leicester, Leicester, LE2 9LX, UK., Karmokar A; Leicester Cancer Research Centre, University of Leicester, Leicester, LE2 9LX, UK., Howells L; Leicester Cancer Research Centre, University of Leicester, Leicester, LE2 9LX, UK., Britton RG; Leicester Cancer Research Centre, University of Leicester, Leicester, LE2 9LX, UK., Parrott E; Leicester Cancer Research Centre, University of Leicester, Leicester, LE2 9LX, UK., Palacios-Gallego R; Leicester Cancer Research Centre, University of Leicester, Leicester, LE2 9LX, UK., Tufarelli C; Leicester Cancer Research Centre, University of Leicester, Leicester, LE2 9LX, UK., Cai H; Leicester Cancer Research Centre, University of Leicester, Leicester, LE2 9LX, UK., Higgins J; Leicester Cancer Research Centre, University of Leicester, Leicester, LE2 9LX, UK., Sylvius N; Genomics Core Laboratory, University of Leicester, Leicester, LE2 7RH, UK., West K; University Hospitals of Leicester, Infirmary Square, Leicester, LE1 5WW, UK., McGregor A; University Hospitals of Leicester, Infirmary Square, Leicester, LE1 5WW, UK., Moore D; Leicester Cancer Research Centre, University of Leicester, Leicester, LE2 9LX, UK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK., Burgess SG; Department of Molecular and Cell Biology, University of Leicester, Leicester, LE2 9LZ, UK; School of Molecular and Cellular Biology, University of Leeds, Leeds, LS2 9JT, UK., Richards MW; Department of Molecular and Cell Biology, University of Leicester, Leicester, LE2 9LZ, UK; School of Molecular and Cellular Biology, University of Leeds, Leeds, LS2 9JT, UK., Winter A; Department of Molecular and Cell Biology, University of Leicester, Leicester, LE2 9LZ, UK; School of Life Sciences, University of Keele, Staffordshire, ST5 5BG, UK., Sidat Z; University Hospitals of Leicester, Infirmary Square, Leicester, LE1 5WW, UK., Foreman N; Leicester Cancer Research Centre, University of Leicester, Leicester, LE2 9LX, UK., Hoorn ST; Laboratory for Experimental Oncology and Radiobiology, Centre for Experimental and Molecular Medicine, Amsterdam UMC, University of Amsterdam, Cancer Centre Amsterdam, Amsterdam, 1105AZ, Netherlands; Oncode Institute, Amsterdam, 1066CX, Netherlands., Vermeulen L; Laboratory for Experimental Oncology and Radiobiology, Centre for Experimental and Molecular Medicine, Amsterdam UMC, University of Amsterdam, Cancer Centre Amsterdam, Amsterdam, 1105AZ, Netherlands; Oncode Institute, Amsterdam, 1066CX, Netherlands., Singh B; University Hospitals of Leicester, Infirmary Square, Leicester, LE1 5WW, UK., Hemingway D; University Hospitals of Leicester, Infirmary Square, Leicester, LE1 5WW, UK., Norwood M; University Hospitals of Leicester, Infirmary Square, Leicester, LE1 5WW, UK., Miller A; University Hospitals of Leicester, Infirmary Square, Leicester, LE1 5WW, UK., Boyle K; University Hospitals of Leicester, Infirmary Square, Leicester, LE1 5WW, UK., Ho C; University Hospitals of Leicester, Infirmary Square, Leicester, LE1 5WW, UK., Aslam MI; University Hospitals of Leicester, Infirmary Square, Leicester, LE1 5WW, UK; University Hospitals Coventry and Warwickshire NHS Trust, Clifford Bridge Road, Coventry, CV2 2DX, UK., Bayliss R; Department of Molecular and Cell Biology, University of Leicester, Leicester, LE2 9LZ, UK; School of Molecular and Cellular Biology, University of Leeds, Leeds, LS2 9JT, UK., Nateri AS; Cancer Genetics and Stem Cell Group, Biodiscovery Institute, Academic Unit of Translational Medical Sciences, School of Medicine, University of Nottingham, Nottingham, NG7 2UH, UK., Rufini A; Leicester Cancer Research Centre, University of Leicester, Leicester, LE2 9LX, UK., Gescher A; Leicester Cancer Research Centre, University of Leicester, Leicester, LE2 9LX, UK., Thomas AL; Leicester Cancer Research Centre, University of Leicester, Leicester, LE2 9LX, UK., Steward WP; Leicester Cancer Research Centre, University of Leicester, Leicester, LE2 9LX, UK., Brown K; Leicester Cancer Research Centre, University of Leicester, Leicester, LE2 9LX, UK. Electronic address: kb20@le.ac.uk.
Source: Cancer letters [Cancer Lett] 2025 Oct 01; Vol. 629, pp. 217885. Date of Electronic Publication: 2025 Jun 19.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7980 (Electronic) Linking ISSN: 03043835 NLM ISO Abbreviation: Cancer Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1872-7980
DOI:10.1016/j.canlet.2025.217885