Discovery and development of a safe and efficient COVID-19 mRNA vaccine, STP2104, using a novel capping library screening method.

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Title: Discovery and development of a safe and efficient COVID-19 mRNA vaccine, STP2104, using a novel capping library screening method.
Authors: Choi K; R&D Center, ST Pharm Co., Ltd., Seoul, Republic of Korea., Lee JY; R&D Center, ST Pharm Co., Ltd., Seoul, Republic of Korea., Kim UI; R&D Center, ST Pharm Co., Ltd., Seoul, Republic of Korea., Park SH; College of Veterinary Medicine, Chungbuk National University, Cheongju-si, Republic of Korea., Hong SH; Department of Microbiology, College of Medicine, Ewha Womens University, Seoul, Republic of Korea., Bang YJ; Department of Medical and Biological Sciences, The Catholic University of Korea, Bucheon-si, Republic of Korea., Hwang YH; Division of Infectious Disease Vaccine Research, Center for Vaccine Research, National Institute of Infectious Diseases, National Institute of Health, Korea Disease Control and Prevention Agency, Cheongju-si, Republic of Korea., Lee JE; Department of Life Science, Sogang University, Seoul, Republic of Korea., Park S; R&D Center, ST Pharm Co., Ltd., Seoul, Republic of Korea., Kim S; College of Veterinary Medicine, Chungbuk National University, Cheongju-si, Republic of Korea., Lee S; R&D Center, ST Pharm Co., Ltd., Seoul, Republic of Korea., Yun YJ; R&D Center, ST Pharm Co., Ltd., Seoul, Republic of Korea., Uhm TG; R&D Center, ST Pharm Co., Ltd., Seoul, Republic of Korea., Lee I; R&D Center, ST Pharm Co., Ltd., Seoul, Republic of Korea., Kwon M; R&D Center, ST Pharm Co., Ltd., Seoul, Republic of Korea., Kwon E; R&D Center, ST Pharm Co., Ltd., Seoul, Republic of Korea., Song S; R&D Center, ST Pharm Co., Ltd., Seoul, Republic of Korea., Kweon Y; R&D Center, ST Pharm Co., Ltd., Seoul, Republic of Korea., Kim H; R&D Center, ST Pharm Co., Ltd., Seoul, Republic of Korea., Oh EY; College of Veterinary Medicine, Chungbuk National University, Cheongju-si, Republic of Korea., Kim JY; Department of Medical and Biological Sciences, The Catholic University of Korea, Bucheon-si, Republic of Korea., Lee TY; Division of Infectious Disease Vaccine Research, Center for Vaccine Research, National Institute of Infectious Diseases, National Institute of Health, Korea Disease Control and Prevention Agency, Cheongju-si, Republic of Korea., Kim SY; Division of Infectious Disease Vaccine Research, Center for Vaccine Research, National Institute of Infectious Diseases, National Institute of Health, Korea Disease Control and Prevention Agency, Cheongju-si, Republic of Korea., Kim SE; Division of Infectious Disease Vaccine Research, Center for Vaccine Research, National Institute of Infectious Diseases, National Institute of Health, Korea Disease Control and Prevention Agency, Cheongju-si, Republic of Korea., Kim YJ; Division of Infectious Disease Vaccine Research, Center for Vaccine Research, National Institute of Infectious Diseases, National Institute of Health, Korea Disease Control and Prevention Agency, Cheongju-si, Republic of Korea., Lee S; Department of Life Science, Sogang University, Seoul, Republic of Korea., Sun R; Department of Life Science, Sogang University, Seoul, Republic of Korea., Lee EJ; Department of Life Science, Sogang University, Seoul, Republic of Korea., Kim G; Department of Life Science, Sogang University, Seoul, Republic of Korea., Lim H; Department of Life Science, Sogang University, Seoul, Republic of Korea., Kim B; R&D Center, ST Pharm Co., Ltd., Seoul, Republic of Korea., Kim J; Department of Life Science, Sogang University, Seoul, Republic of Korea., Kim D; Division of Infectious Disease Vaccine Research, Center for Vaccine Research, National Institute of Infectious Diseases, National Institute of Health, Korea Disease Control and Prevention Agency, Cheongju-si, Republic of Korea., Nam JH; Department of Medical and Biological Sciences, The Catholic University of Korea, Bucheon-si, Republic of Korea., Lee SM; College of Veterinary Medicine, Chungbuk National University, Cheongju-si, Republic of Korea., Kim K; R&D Center, ST Pharm Co., Ltd., Seoul, Republic of Korea., Yang JS; R&D Center, ST Pharm Co., Ltd., Seoul, Republic of Korea.
Source: Frontiers in immunology [Front Immunol] 2025 Jun 09; Vol. 16, pp. 1571713. Date of Electronic Publication: 2025 Jun 09 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2025.1571713