Kininogen enhances seizure susceptibility in mice possibly through bradykinin-induced modulation of calcium transients in glutamatergic and GABAergic neurons.

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Title: Kininogen enhances seizure susceptibility in mice possibly through bradykinin-induced modulation of calcium transients in glutamatergic and GABAergic neurons.
Authors: Ghosh A; Bio-X Institutes, Key Laboratory for the Genetics of Development & Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China.; School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China., Huang J; Bio-X Institutes, Key Laboratory for the Genetics of Development & Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China.; School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China., Wang Q; Bio-X Institutes, Key Laboratory for the Genetics of Development & Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China.; School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China., Gong Y; Bio-X Institutes, Key Laboratory for the Genetics of Development & Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China.; School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China., Jain S; Advanced Technology Development Centre, Indian Institute of Technology Kharagpur, West Bengal, India.; Information Processing Laboratory, Department of Electronics and Electrical Communication Engineering, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal, India., Thakur A; Department of Pharmacology, Delhi Pharmaceutical Sciences and Research University, Delhi, India.; Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States., De A; Advanced Technology Development Centre, Indian Institute of Technology Kharagpur, West Bengal, India.; Information Processing Laboratory, Department of Electronics and Electrical Communication Engineering, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal, India., Gong M; Bio-X Institutes, Key Laboratory for the Genetics of Development & Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China.; School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China., Kiyohara Y; Bio-X Institutes, Key Laboratory for the Genetics of Development & Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China.; School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China., Hu J; No. 2 High School of East China Normal University, Zizhu, Shanghai, China., Jin L; Shanghai Fifth People's Hospital, Fudan University, Shanghai, China., Bandyopadhyay S; Advanced Technology Development Centre, Indian Institute of Technology Kharagpur, West Bengal, India.; Information Processing Laboratory, Department of Electronics and Electrical Communication Engineering, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal, India., Chen F; Department of Pharmacy, the First Affiliated Hospital of Xiamen University, Xiamen, China., Li S; Bio-X Institutes, Key Laboratory for the Genetics of Development & Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China.
Source: Frontiers in pharmacology [Front Pharmacol] 2025 Jun 10; Vol. 16, pp. 1509837. Date of Electronic Publication: 2025 Jun 10 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:1663-9812
DOI:10.3389/fphar.2025.1509837