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The rs3757385 polymorphism increases IRF5 expression and systemic nitric oxide metabolites, protecting urothelial bladder cancer patients from recurrence.

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Title: The rs3757385 polymorphism increases IRF5 expression and systemic nitric oxide metabolites, protecting urothelial bladder cancer patients from recurrence.
Authors: Souza AP; Laboratory of Mutagenesis and Oncogenetics, Department of General Biology, Center of Biological Sciences, State University of Londrina (UEL), Londrina, 86057-970, Brazil., Silva IM; Laboratory of Mutagenesis and Oncogenetics, Department of General Biology, Center of Biological Sciences, State University of Londrina (UEL), Londrina, 86057-970, Brazil., Vacario BGL; Laboratory of Mutagenesis and Oncogenetics, Department of General Biology, Center of Biological Sciences, State University of Londrina (UEL), Londrina, 86057-970, Brazil., Koike A; Londrina Cancer Hospital, Londrina, 86015-520, Brazil., Paz RG; Laboratory of Tumor Biology, Health Sciences Center, State University of West Paraná (UNIOESTE), Francisco Beltrão, PR, 85605-010, Brazil., Coradi C; Laboratory of Tumor Biology, Health Sciences Center, State University of West Paraná (UNIOESTE), Francisco Beltrão, PR, 85605-010, Brazil., Wrzesinski EMS; Laboratory of Tumor Biology, Health Sciences Center, State University of West Paraná (UNIOESTE), Francisco Beltrão, PR, 85605-010, Brazil., Trigo GL; Laboratory of Research in Applied Immunology, Department of Pathology, Clinical Analysis and Toxicology, Health Sciences Center, University of Londrina, Londrina, Paraná, 86038-440, Brazil., Simão ANC; Laboratory of Research in Applied Immunology, Department of Pathology, Clinical Analysis and Toxicology, Health Sciences Center, University of Londrina, Londrina, Paraná, 86038-440, Brazil., Lozovoy MAB; Laboratory of Research in Applied Immunology, Department of Pathology, Clinical Analysis and Toxicology, Health Sciences Center, University of Londrina, Londrina, Paraná, 86038-440, Brazil., Guembarovski RL; Laboratory of Mutagenesis and Oncogenetics, Department of General Biology, Center of Biological Sciences, State University of Londrina (UEL), Londrina, 86057-970, Brazil., Panis C; Laboratory of Tumor Biology, Health Sciences Center, State University of West Paraná (UNIOESTE), Francisco Beltrão, PR, 85605-010, Brazil., Serpeloni JM; Laboratory of Mutagenesis and Oncogenetics, Department of General Biology, Center of Biological Sciences, State University of Londrina (UEL), Londrina, 86057-970, Brazil. julianaserpeloni@uel.br.
Source: Molecular biology reports [Mol Biol Rep] 2025 Jun 28; Vol. 52 (1), pp. 649. Date of Electronic Publication: 2025 Jun 28.
Publication Type: Journal Article
Journal Info: Publisher: Reidel Country of Publication: Netherlands NLM ID: 0403234 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-4978 (Electronic) Linking ISSN: 03014851 NLM ISO Abbreviation: Mol Biol Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1573-4978
DOI:10.1007/s11033-025-10738-2