Decreased non-neurogenic acetylcholine in bone marrow triggers age-related defective stem/progenitor cell homing.
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| Title: | Decreased non-neurogenic acetylcholine in bone marrow triggers age-related defective stem/progenitor cell homing. |
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| Authors: | Morikawa T; Department of Stem Cell Biology, National Institute of Global Health and Medicine, Japan Institute for Health Security, Tokyo, Japan., Fujita S; Department of Stem Cell Biology, National Institute of Global Health and Medicine, Japan Institute for Health Security, Tokyo, Japan., Sugiura Y; Multiomics Platform, Center for Cancer Immunotherapy and Immunobiology, Kyoto University Graduate School of Medicine, Kyoto, Japan.; WPI-Bio2Q Research Center, Keio University, Tokyo, Japan., Tamaki S; Department of Stem Cell Biology, National Institute of Global Health and Medicine, Japan Institute for Health Security, Tokyo, Japan., Haraguchi M; Department of Stem Cell Biology, National Institute of Global Health and Medicine, Japan Institute for Health Security, Tokyo, Japan.; Kanagawa Institute of Industrial Science and Technology (KISTEC), Kawasaki, Kanagawa, Japan., Shiroshita K; Department of Stem Cell Biology, National Institute of Global Health and Medicine, Japan Institute for Health Security, Tokyo, Japan., Watanuki S; Department of Stem Cell Biology, National Institute of Global Health and Medicine, Japan Institute for Health Security, Tokyo, Japan.; Department of Cell Fate Biology and Stem Cell Medicine, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan., Kobayashi H; Department of Stem Cell Biology, National Institute of Global Health and Medicine, Japan Institute for Health Security, Tokyo, Japan.; Department of Cell Fate Biology and Stem Cell Medicine, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan., Kanai-Sudo H; Department of Stem Cell Biology, National Institute of Global Health and Medicine, Japan Institute for Health Security, Tokyo, Japan., Naito Y; Clinical Translational Research Center, Keio University Hospital, Tokyo, Japan., Hayakawa N; Central Institute for Experimental Medicine and Life Science, Kawasaki, Kanagawa, Japan., Matsuura T; Clinical Translational Research Center, Keio University Hospital, Tokyo, Japan., Hishiki T; Department of Health Chemistry, Showa Pharmaceutical University, Machida, Tokyo, Japan., Matsui M; Yokokawa Ladies Clinic, Tokyo, Japan., Tsutsui M; Department of Pharmacology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan., Suematsu M; WPI-Bio2Q Research Center, Keio University, Tokyo, Japan.; Central Institute for Experimental Medicine and Life Science, Kawasaki, Kanagawa, Japan., Takubo K; Department of Stem Cell Biology, National Institute of Global Health and Medicine, Japan Institute for Health Security, Tokyo, Japan. keiyot@gmail.com.; Department of Cell Fate Biology and Stem Cell Medicine, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan. keiyot@gmail.com.; Japan Agency for Medical Research and Development (AMED), Core Research for Evolutional Science and Technology (CREST), Tokyo, Japan. keiyot@gmail.com. |
| Source: | Nature communications [Nat Commun] 2025 Jul 01; Vol. 16 (1), pp. 5475. Date of Electronic Publication: 2025 Jul 01. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-60515-9 |
