BMAL1 and ARNT enable circadian HIF2α responses in clear cell renal cell carcinoma.

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Title: BMAL1 and ARNT enable circadian HIF2α responses in clear cell renal cell carcinoma.
Authors: Mello RM; Department of Molecular and Cellular Biology, Scripps Research Institute, La Jolla, CA, USA.; Department of Molecular Medicine, Scripps Research Institute, La Jolla, CA, USA., Gomez Ceballos D; Department of Molecular and Cellular Biology, Scripps Research Institute, La Jolla, CA, USA.; Department of Molecular Medicine, Scripps Research Institute, La Jolla, CA, USA., Sandate CR; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland., Wang S; Department of Molecular and Cellular Biology, Scripps Research Institute, La Jolla, CA, USA.; Department of Molecular Medicine, Scripps Research Institute, La Jolla, CA, USA., Jouffe C; Institute for Diabetes and Endocrinology (IDE), Helmholtz Munich, Neuherberg, Germany.; Institute for Diabetes and Cancer (IDC), Helmholtz Munich, Neuherberg, Germany., Agudelo D; Institute for Diabetes and Endocrinology (IDE), Helmholtz Munich, Neuherberg, Germany., Uhlenhaut NH; Institute for Diabetes and Endocrinology (IDE), Helmholtz Munich, Neuherberg, Germany.; Metabolic Programming, TUM School of Life Sciences & ZIEL Institute for Food and Health, Freising, Germany., Thomä NH; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland., Simon MC; Perelman School of Medicine, Abramson Family Cancer Research Institute, Philadelphia, PA, USA.; Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA, USA., Lamia KA; Department of Molecular and Cellular Biology, Scripps Research Institute, La Jolla, CA, USA. klamia@scripps.edu.; Department of Molecular Medicine, Scripps Research Institute, La Jolla, CA, USA. klamia@scripps.edu.
Source: Nature communications [Nat Commun] 2025 Jul 01; Vol. 16 (1), pp. 5834. Date of Electronic Publication: 2025 Jul 01.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-60904-0