Combining MRI radiomics, hypoxia gene signature score and clinical variables for prediction of biochemical recurrence-free survival after radiotherapy in prostate cancer.

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Title: Combining MRI radiomics, hypoxia gene signature score and clinical variables for prediction of biochemical recurrence-free survival after radiotherapy in prostate cancer.
Authors: Zhong J; Leeds Institute of Medical Research, University of Leeds, Leeds, UK. jim.zhong@nhs.net.; Department of Radiology, Leeds Cancer Centre, St James's University Hospital, Leeds Teaching Hospitals National Health Service (NHS) Trust, Beckett Street, Leeds, LS9 7TF, UK. jim.zhong@nhs.net., Davey A; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Department of Radiotherapy Related Research, The Christie NHS Foundation Trust, Manchester, UK., Frood R; Department of Radiology, Leeds Cancer Centre, St James's University Hospital, Leeds Teaching Hospitals National Health Service (NHS) Trust, Beckett Street, Leeds, LS9 7TF, UK.; Leeds Cancer Research UK Clinical Trials Unit, Trials Research, Leeds Institute of Clinical, University of Leeds, Leeds, UK., McWilliam A; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Department of Radiotherapy Related Research, The Christie NHS Foundation Trust, Manchester, UK., Shortall J; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Department of Radiotherapy Related Research, The Christie NHS Foundation Trust, Manchester, UK., Reardon M; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Department of Radiotherapy Related Research, The Christie NHS Foundation Trust, Manchester, UK., Reaves K; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Department of Radiotherapy Related Research, The Christie NHS Foundation Trust, Manchester, UK., Swinton M; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Department of Radiotherapy Related Research, The Christie NHS Foundation Trust, Manchester, UK., Hulson O; Department of Radiology, Leeds Cancer Centre, St James's University Hospital, Leeds Teaching Hospitals National Health Service (NHS) Trust, Beckett Street, Leeds, LS9 7TF, UK., West C; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK., Buckley D; Leeds Institute of Medical Research, University of Leeds, Leeds, UK., Brown S; Leeds Cancer Research UK Clinical Trials Unit, Trials Research, Leeds Institute of Clinical, University of Leeds, Leeds, UK., Choudhury A; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Department of Radiotherapy Related Research, The Christie NHS Foundation Trust, Manchester, UK., Hoskin P; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Department of Radiotherapy Related Research, The Christie NHS Foundation Trust, Manchester, UK., Henry A; Leeds Institute of Medical Research, University of Leeds, Leeds, UK.; Department of Clinical Oncology, Leeds Cancer Centre, St James's University Hospital, Leeds Teaching Hospitals NHS Trust, Beckett Street, Leeds, LS9 7TF, UK., Scarsbrook A; Leeds Institute of Medical Research, University of Leeds, Leeds, UK.; Department of Radiology, Leeds Cancer Centre, St James's University Hospital, Leeds Teaching Hospitals National Health Service (NHS) Trust, Beckett Street, Leeds, LS9 7TF, UK.
Source: La Radiologia medica [Radiol Med] 2025 Aug; Vol. 130 (8), pp. 1139-1148. Date of Electronic Publication: 2025 Jul 02.
Publication Type: Journal Article
Journal Info: Publisher: Springer Milan Country of Publication: Italy NLM ID: 0177625 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1826-6983 (Electronic) Linking ISSN: 00338362 NLM ISO Abbreviation: Radiol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1826-6983
DOI:10.1007/s11547-025-02037-4