View in EDS HTML Full Text PDF Full Text

Induction of lung mucosal immunity by a next-generation inhaled aerosol COVID-19 vaccine: an open-label, multi-arm phase 1 clinical trial.

Saved in:
Bibliographic Details
Title: Induction of lung mucosal immunity by a next-generation inhaled aerosol COVID-19 vaccine: an open-label, multi-arm phase 1 clinical trial.
Authors: Jeyanathan M; McMaster Immunology Research Centre, McMaster University, Hamilton, ON, Canada.; Department of Medicine, McMaster University, Hamilton, ON, Canada.; Global Nexus School for Pandemic Prevention and Response, McMaster University, Hamilton, ON, Canada., Afkhami S; McMaster Immunology Research Centre, McMaster University, Hamilton, ON, Canada.; Global Nexus School for Pandemic Prevention and Response, McMaster University, Hamilton, ON, Canada.; Department of Biochemistry & Biomedical Sciences, McMaster University, Hamilton, ON, Canada., D'Agostino MR; McMaster Immunology Research Centre, McMaster University, Hamilton, ON, Canada.; Global Nexus School for Pandemic Prevention and Response, McMaster University, Hamilton, ON, Canada.; Department of Biochemistry & Biomedical Sciences, McMaster University, Hamilton, ON, Canada., Satia I; Department of Medicine, McMaster University, Hamilton, ON, Canada., Fritz DK; McMaster Immunology Research Centre, McMaster University, Hamilton, ON, Canada.; Department of Medicine, McMaster University, Hamilton, ON, Canada.; Global Nexus School for Pandemic Prevention and Response, McMaster University, Hamilton, ON, Canada., Miyasaki K; McMaster Immunology Research Centre, McMaster University, Hamilton, ON, Canada.; Department of Medicine, McMaster University, Hamilton, ON, Canada.; Global Nexus School for Pandemic Prevention and Response, McMaster University, Hamilton, ON, Canada., Ang JC; McMaster Immunology Research Centre, McMaster University, Hamilton, ON, Canada.; Global Nexus School for Pandemic Prevention and Response, McMaster University, Hamilton, ON, Canada.; Department of Biochemistry & Biomedical Sciences, McMaster University, Hamilton, ON, Canada., Zganiacz A; McMaster Immunology Research Centre, McMaster University, Hamilton, ON, Canada.; Department of Medicine, McMaster University, Hamilton, ON, Canada.; Global Nexus School for Pandemic Prevention and Response, McMaster University, Hamilton, ON, Canada., Howie KJ; Department of Medicine, McMaster University, Hamilton, ON, Canada., Swinton M; McMaster Immunology Research Centre, McMaster University, Hamilton, ON, Canada.; Global Nexus School for Pandemic Prevention and Response, McMaster University, Hamilton, ON, Canada.; Department of Pathology & Molecular Medicine, McMaster University, Hamilton, ON, Canada., Aguirre E; Department of Pathology & Molecular Medicine, McMaster University, Hamilton, ON, Canada., Zheng MB; McMaster Immunology Research Centre, McMaster University, Hamilton, ON, Canada.; Department of Medicine, McMaster University, Hamilton, ON, Canada.; Global Nexus School for Pandemic Prevention and Response, McMaster University, Hamilton, ON, Canada., Kazhdan N; McMaster Immunology Research Centre, McMaster University, Hamilton, ON, Canada.; Department of Medicine, McMaster University, Hamilton, ON, Canada.; Global Nexus School for Pandemic Prevention and Response, McMaster University, Hamilton, ON, Canada., Dvorkin-Gheva A; McMaster Immunology Research Centre, McMaster University, Hamilton, ON, Canada.; Department of Medicine, McMaster University, Hamilton, ON, Canada., Mbuagbaw L; Department of Health Research Methodology, Evidence and Impact, McMaster University, Hamilton, ON, Canada., Medina MFC; McMaster Immunology Research Centre, McMaster University, Hamilton, ON, Canada.; Department of Medicine, McMaster University, Hamilton, ON, Canada.; Global Nexus School for Pandemic Prevention and Response, McMaster University, Hamilton, ON, Canada., Diab N; Department of Medicine, McMaster University, Hamilton, ON, Canada., Brister DL; Department of Medicine, McMaster University, Hamilton, ON, Canada., Gauvreau GM; Department of Medicine, McMaster University, Hamilton, ON, Canada., Lichty BD; McMaster Immunology Research Centre, McMaster University, Hamilton, ON, Canada. lichtyb@mcmaster.ca.; Department of Medicine, McMaster University, Hamilton, ON, Canada. lichtyb@mcmaster.ca.; Global Nexus School for Pandemic Prevention and Response, McMaster University, Hamilton, ON, Canada. lichtyb@mcmaster.ca., Miller MS; McMaster Immunology Research Centre, McMaster University, Hamilton, ON, Canada. mmiller@mcmaster.ca.; Global Nexus School for Pandemic Prevention and Response, McMaster University, Hamilton, ON, Canada. mmiller@mcmaster.ca.; Department of Biochemistry & Biomedical Sciences, McMaster University, Hamilton, ON, Canada. mmiller@mcmaster.ca., Smaill F; McMaster Immunology Research Centre, McMaster University, Hamilton, ON, Canada. smaill@mcmaster.ca.; Global Nexus School for Pandemic Prevention and Response, McMaster University, Hamilton, ON, Canada. smaill@mcmaster.ca.; Department of Pathology & Molecular Medicine, McMaster University, Hamilton, ON, Canada. smaill@mcmaster.ca., Xing Z; McMaster Immunology Research Centre, McMaster University, Hamilton, ON, Canada. xingz@mcmaster.ca.; Department of Medicine, McMaster University, Hamilton, ON, Canada. xingz@mcmaster.ca.; Global Nexus School for Pandemic Prevention and Response, McMaster University, Hamilton, ON, Canada. xingz@mcmaster.ca.
Source: Nature communications [Nat Commun] 2025 Jul 02; Vol. 16 (1), pp. 6000. Date of Electronic Publication: 2025 Jul 02.
Publication Type: Journal Article; Clinical Trial, Phase I
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
Description
ISSN:2041-1723
DOI:10.1038/s41467-025-60726-0