Quantitative characterisation of extracellular vesicles designed to decoy or compete with SARS-CoV-2 reveals differential mode of action across variants of concern and highlights the diversity of Omicron.
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| Title: | Quantitative characterisation of extracellular vesicles designed to decoy or compete with SARS-CoV-2 reveals differential mode of action across variants of concern and highlights the diversity of Omicron. |
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| Authors: | Schürz M; Chemical Biology and Biological Therapeutics, Department of Biosciences and Medical Biology, Paris Lodron University Salzburg, Salzburg, Austria.; Ludwig Boltzmann Institute for Nanovesicular Precision Medicine at the Paris Lodron University Salzburg, Salzburg, Austria., Pagani I; Viral Pathogenesis and Biosafety Unit, Division of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy., Klinglmayr E; Chemical Biology and Biological Therapeutics, Department of Biosciences and Medical Biology, Paris Lodron University Salzburg, Salzburg, Austria.; Ludwig Boltzmann Institute for Nanovesicular Precision Medicine at the Paris Lodron University Salzburg, Salzburg, Austria.; GMP Laboratory, Paracelsus Medical University Salzburg, Salzburg, Austria., Melo Benirschke H; Chemical Biology and Biological Therapeutics, Department of Biosciences and Medical Biology, Paris Lodron University Salzburg, Salzburg, Austria., Mayora Neto M; Viral Pseudotype Unit, Medway School of Pharmacy, University of Kent, Canterbury, UK., Galietta LJV; Department of Translational Medical Sciences, Telethon Institute of Genetics and Medicine, University of Napoli'Federico II,'Naples, Pozzuoli, Italy., Venturini A; Department of Translational Medical Sciences, Telethon Institute of Genetics and Medicine, University of Napoli'Federico II,'Naples, Pozzuoli, Italy., Pedemonte N; UOC Genetica Medica, IRCCS Istituto Giannina Gaslini, Genova, Italy., Capurro V; UOC Genetica Medica, IRCCS Istituto Giannina Gaslini, Genova, Italy., Laner-Plamberger S; Department for Transfusion Medicine, University Hospital of Salzburg, Salzburg, Austria., Grabmer C; Department for Transfusion Medicine, University Hospital of Salzburg, Salzburg, Austria., Emminger E; Cell Therapy Institute, Paracelsus Medical University, Salzburg, Austria., Wolf M; Cell Therapy Institute, Paracelsus Medical University, Salzburg, Austria., Steiner M; Chemical Biology and Biological Therapeutics, Department of Biosciences and Medical Biology, Paris Lodron University Salzburg, Salzburg, Austria., Kohlmetz C; Chemical Biology and Biological Therapeutics, Department of Biosciences and Medical Biology, Paris Lodron University Salzburg, Salzburg, Austria., Mayr N; Chemical Biology and Biological Therapeutics, Department of Biosciences and Medical Biology, Paris Lodron University Salzburg, Salzburg, Austria., Paniushkina L; Cell Therapy Institute, Paracelsus Medical University, Salzburg, Austria., Schallmoser K; Department for Transfusion Medicine, University Hospital of Salzburg, Salzburg, Austria., Strunk D; Cell Therapy Institute, Paracelsus Medical University, Salzburg, Austria., Brandstetter H; Chemical Biology and Biological Therapeutics, Department of Biosciences and Medical Biology, Paris Lodron University Salzburg, Salzburg, Austria., Hintersteiner M; EvoBiotiX SA, Lugano, Switzerland., Temperton N; Viral Pseudotype Unit, Medway School of Pharmacy, University of Kent, Canterbury, UK., Vicenzi E; Viral Pathogenesis and Biosafety Unit, Division of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy. vicenzi.elisa@hsr.it., Meisner-Kober N; Chemical Biology and Biological Therapeutics, Department of Biosciences and Medical Biology, Paris Lodron University Salzburg, Salzburg, Austria. nicole.meisner-kober@plus.ac.at.; Ludwig Boltzmann Institute for Nanovesicular Precision Medicine at the Paris Lodron University Salzburg, Salzburg, Austria. nicole.meisner-kober@plus.ac.at. |
| Source: | Cell communication and signaling : CCS [Cell Commun Signal] 2025 Jul 02; Vol. 23 (1), pp. 323. Date of Electronic Publication: 2025 Jul 02. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X (Electronic) Linking ISSN: 1478811X NLM ISO Abbreviation: Cell Commun Signal Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1478-811X |
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| DOI: | 10.1186/s12964-025-02223-x |
