Rationale, design and baseline characteristics of REMODEL, a mechanism-of-action trial with semaglutide in people with type 2 diabetes and chronic kidney disease.

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Title: Rationale, design and baseline characteristics of REMODEL, a mechanism-of-action trial with semaglutide in people with type 2 diabetes and chronic kidney disease.
Authors: Cherney DZI; Department of Medicine, Division of Nephrology, University Health Network, Toronto, Ontario, Canada., Belmar N; Novo Nordisk A/S, Søborg, Denmark., Bjornstad P; Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, and Division of Endocrinology, Department of Pediatrics, University of Washington, Seattle, WA, USA.; Division of Renal Diseases and Hypertension, Department of Medicine, Section of Pediatric Endocrinology, Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Chacko MM; Novo Nordisk GBS India, Bangalore, India., Gunnarsson TP; Novo Nordisk A/S, Søborg, Denmark., Hodgin JB; Department of Pathology and Clinical Laboratories, University of Michigan, Ann Arbor, MI, USA., Kretzler M; Department of Internal Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Pruijm M; Service of Nephrology, University Hospital of Lausanne and University of Lausanne, Lausanne, Switzerland., Schytz PA; Novo Nordisk A/S, Søborg, Denmark., Tuttle KR; Providence Medical Research Center, Providence Inland Northwest Health, Spokane WA, USA.; Kidney Research Institute and Nephrology Division, University of Washington School of Medicine, Seattle, WA, USA.
Source: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association [Nephrol Dial Transplant] 2025 Oct 30; Vol. 40 (11), pp. 2182-2192.
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 8706402 Publication Model: Print Cited Medium: Internet ISSN: 1460-2385 (Electronic) Linking ISSN: 09310509 NLM ISO Abbreviation: Nephrol Dial Transplant Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1460-2385
DOI:10.1093/ndt/gfaf114