Rationale, design and baseline characteristics of REMODEL, a mechanism-of-action trial with semaglutide in people with type 2 diabetes and chronic kidney disease.

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Title: Rationale, design and baseline characteristics of REMODEL, a mechanism-of-action trial with semaglutide in people with type 2 diabetes and chronic kidney disease.
Authors: Cherney DZI; Department of Medicine, Division of Nephrology, University Health Network, Toronto, Ontario, Canada., Belmar N; Novo Nordisk A/S, Søborg, Denmark., Bjornstad P; Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, and Division of Endocrinology, Department of Pediatrics, University of Washington, Seattle, WA, USA.; Division of Renal Diseases and Hypertension, Department of Medicine, Section of Pediatric Endocrinology, Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Chacko MM; Novo Nordisk GBS India, Bangalore, India., Gunnarsson TP; Novo Nordisk A/S, Søborg, Denmark., Hodgin JB; Department of Pathology and Clinical Laboratories, University of Michigan, Ann Arbor, MI, USA., Kretzler M; Department of Internal Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Pruijm M; Service of Nephrology, University Hospital of Lausanne and University of Lausanne, Lausanne, Switzerland., Schytz PA; Novo Nordisk A/S, Søborg, Denmark., Tuttle KR; Providence Medical Research Center, Providence Inland Northwest Health, Spokane WA, USA.; Kidney Research Institute and Nephrology Division, University of Washington School of Medicine, Seattle, WA, USA.
Source: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association [Nephrol Dial Transplant] 2025 Oct 30; Vol. 40 (11), pp. 2182-2192.
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 8706402 Publication Model: Print Cited Medium: Internet ISSN: 1460-2385 (Electronic) Linking ISSN: 09310509 NLM ISO Abbreviation: Nephrol Dial Transplant Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Rationale, design and baseline characteristics of REMODEL, a mechanism-of-action trial with semaglutide in people with type 2 diabetes and chronic kidney disease.
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  Data: <searchLink fieldCode="AU" term="%22Cherney+DZI%22">Cherney DZI</searchLink>; Department of Medicine, Division of Nephrology, University Health Network, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Belmar+N%22">Belmar N</searchLink>; Novo Nordisk A/S, Søborg, Denmark.<br /><searchLink fieldCode="AU" term="%22Bjornstad+P%22">Bjornstad P</searchLink>; Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, and Division of Endocrinology, Department of Pediatrics, University of Washington, Seattle, WA, USA.; Division of Renal Diseases and Hypertension, Department of Medicine, Section of Pediatric Endocrinology, Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Chacko+MM%22">Chacko MM</searchLink>; Novo Nordisk GBS India, Bangalore, India.<br /><searchLink fieldCode="AU" term="%22Gunnarsson+TP%22">Gunnarsson TP</searchLink>; Novo Nordisk A/S, Søborg, Denmark.<br /><searchLink fieldCode="AU" term="%22Hodgin+JB%22">Hodgin JB</searchLink>; Department of Pathology and Clinical Laboratories, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Kretzler+M%22">Kretzler M</searchLink>; Department of Internal Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Pruijm+M%22">Pruijm M</searchLink>; Service of Nephrology, University Hospital of Lausanne and University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Schytz+PA%22">Schytz PA</searchLink>; Novo Nordisk A/S, Søborg, Denmark.<br /><searchLink fieldCode="AU" term="%22Tuttle+KR%22">Tuttle KR</searchLink>; Providence Medical Research Center, Providence Inland Northwest Health, Spokane WA, USA.; Kidney Research Institute and Nephrology Division, University of Washington School of Medicine, Seattle, WA, USA.
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  Data: <searchLink fieldCode="JN" term="%228706402%22">Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association</searchLink> [Nephrol Dial Transplant] 2025 Oct 30; Vol. 40 (11), pp. 2182-2192.
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  Data: Journal Article; Clinical Trial Protocol
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8706402 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1460-2385 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209310509%22">09310509 </searchLink><i>NLM ISO Abbreviation: </i>Nephrol Dial Transplant <i>Subsets: </i>MEDLINE
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        Value: 10.1093/ndt/gfaf114
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        Text: English
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              Text: 2025 Oct 30
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