A cohort of mRNAs undergo high-stoichiometry NSUN6-mediated site-specific m5C modification.

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Title: A cohort of mRNAs undergo high-stoichiometry NSUN6-mediated site-specific m5C modification.
Authors: Zhang YY; School of Life Science and Technology, ShanghaiTech University, Shanghai, China., Li CT; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.; State Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Beijing, China., Zhou YJ; School of Life Science and Technology, ShanghaiTech University, Shanghai, China., Li H; School of Life Science and Technology, ShanghaiTech University, Shanghai, China., Li J; School of Life Science and Technology, ShanghaiTech University, Shanghai, China., Xiong QP; State Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Beijing, China., Zhou W; School of Life Science and Technology, ShanghaiTech University, Shanghai, China., Huang W; MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing, China., Zhang QC; MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing, China., Xiang Y; School of Life Science and Technology, ShanghaiTech University, Shanghai, China., Wang ED; School of Life Science and Technology, ShanghaiTech University, Shanghai, China. edwang@sibcb.ac.cn.; State Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Beijing, China. edwang@sibcb.ac.cn., Xu B; Center for Applied Bioinformatics, St. Jude Children's Research Hospital, Memphis, TN, USA. Beisi.Xu@STJUDE.ORG., Liu RJ; School of Life Science and Technology, ShanghaiTech University, Shanghai, China. liurj@shanghaitech.edu.cn.
Source: Nature communications [Nat Commun] 2025 Jul 04; Vol. 16 (1), pp. 6119. Date of Electronic Publication: 2025 Jul 04.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-60873-4