NOTCH1 reverses immune suppression in small cell lung cancer through reactivation of STING.

Saved in:
Bibliographic Details
Title: NOTCH1 reverses immune suppression in small cell lung cancer through reactivation of STING.
Authors: Kim YS; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Nabet BY; Genentech Inc., South San Francisco, California, USA., Cortez BN; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Sun NY; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Sebastian R; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Redon CE; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Ray A; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Liu L; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Ishola AA; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Loew S; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Dhall A; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Sindiri S; Surgery Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Gayevskiy V; Genentech Inc., South San Francisco, California, USA.; Rancho Biosciences, San Diego, California, USA., Lee MJ; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Rastogi S; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Sato N; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Kedei N; Collaborative Protein Technology Resource, Center for Cancer Research, and., Andresson T; Protein Characterization Laboratory, National Cancer Institute, Bethesda, Maryland, USA., Das S; Protein Characterization Laboratory, National Cancer Institute, Bethesda, Maryland, USA., Kumar S; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Bers AE; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Zhang H; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Chiappori A; Thoracic Oncology Program, Moffitt Cancer Center, Tampa, Florida, USA., Gopal P; Department of Radiation Oncology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Abazeed ME; Department of Radiation Oncology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Chen H; Division of Oncology, Department of Medicine, Washington University in St. Louis, St. Louis, Missouri, USA., Aladjem MI; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Pommier Y; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Velez MJ; Department of Pathology and Laboratory Medicine, University of Rochester, Rochester, New York, USA., Shames DS; Genentech Inc., South San Francisco, California, USA., Roper N; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA.
Source: The Journal of clinical investigation [J Clin Invest] 2025 Jul 08; Vol. 135 (18). Date of Electronic Publication: 2025 Jul 08 (Print Publication: 2025).
Publication Type: Journal Article; Clinical Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: eCollection Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1558-8238
DOI:10.1172/JCI185423