GWAS meta-analysis identifies five susceptibility loci for endometrial cancer.

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Bibliographic Details
Title: GWAS meta-analysis identifies five susceptibility loci for endometrial cancer.
Authors: Ramachandran D; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Wang X; Cancer Research Program, QIMR Berghofer, Brisbane, Queensland, Australia., Laisk T; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Zheng Y; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany; Department of Gynecology, The First Hospital of Hebei Medical University, Shijiazhuang, China., Ingold N; Cancer Research Program, QIMR Berghofer, Brisbane, Queensland, Australia., Canson DM; Population Health Program, QIMR Berghofer, Brisbane, Queensland, Australia., Kho PF; Cancer Research Program, QIMR Berghofer, Brisbane, Queensland, Australia., Naumann BJ; Cancer Research Program, QIMR Berghofer, Brisbane, Queensland, Australia; School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia., Chapman CJ; Cancer Research Program, QIMR Berghofer, Brisbane, Queensland, Australia., Bousset K; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Krause AV; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Schürmann P; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Wieland B; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Hanel P; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Hülse F; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Häfner N; Department of Gynaecology, Jena University Hospital - Friedrich Schiller University, Jena, Germany., Runnebaum I; Department of Gynaecology, Jena University Hospital - Friedrich Schiller University, Jena, Germany; RU21 GmbH, Jena, Germany., Dubrowinskaja N; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany; Clinic for Rheumatology and Immunology, Hannover Medical School, Hannover, Germany., Turmanov N; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany; Rahat Clinics, Almaty, Kazakhstan; KRH Clinic Neustadt am Rübenberge, Neustadt am Rübenberge, Germany., Yugay T; Rahat Clinics, Almaty, Kazakhstan., Yessimsiitova ZB; Department of Biodiversity and Bioresources, al-Farabi Kazakh National University, Almaty, Kazakhstan., Amant F; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University Hospitals KU Leuven, University of Leuven, Leuven, Belgium; Gynecological Oncology Laboratory, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium., Annibali D; Gynecological Oncology Laboratory, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium., Beckmann MW; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany., Bodelon C; Department of Population Science, American Cancer Society, Atlanta, GA, USA., Buchanan DD; Colorectal Oncogenomics Group, Department of Clinical Pathology, Melbourne Medical School, The University of Melbourne, Melbourne, Victoria, Australia; Collaborative Centre for Genomic Cancer Medicine, Victorian Comprehensive Cancer Centre, Parkville, Victoria, Australia., Chen C; Epidemiology Program, Fred Hutchinson Cancer Center, Seattle, WA, USA., Clarke MA; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., Cook LS; Epidemiology, School of Public Health, University of Colorado, Aurora, CO, USA; Community Health Sciences, University of Calgary, Calgary, AB, Canada., De Vivo I; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA., De Wispelaere W; Gynecological Oncology Laboratory, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium., Du M; Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA., Easton DF; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK., Emons J; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany., Fasching PA; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany., Friedenreich CM; Department of Cancer Epidemiology and Prevention Research, Alberta Health Services, Calgary, AB, Canada; Departments of Oncology and Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada., Gallagher G; Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA., Giles GG; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia., Goode EL; Division of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Harris HR; Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA; Department of Epidemiology, University of Washington, Seattle, WA, USA., Hunter DJ; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Kolin DL; Brigham and Women's Hospital, Boston, MA, USA., Kraft P; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Lacey JV; Department of Computational and Quantitative Medicine, City of Hope, Duarte, CA, USA; City of Hope Comprehensive Cancer Center, City of Hope, Duarte, CA, USA., Lambrechts D; Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium; VIB Center for Cancer Biology, VIB, Leuven, Belgium., Lu L; Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT, USA., Mutter GL; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Naduparambil J; Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA., O'Connell K; Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA., Patel AV; Department of Population Science, American Cancer Society, Atlanta, GA, USA., Pharoah PDP; Department of Computational Biomedicine, Cedars-Sinai Medical Center, West Hollywood, CA, USA., Rebbeck TR; Harvard T.H. Chan School of Public Health, Boston, MA, USA; Dana-Farber Cancer Institute, Boston, MA, USA., Ricceri F; Department of Clinical and Biological Sciences, Centre for Biostatistics, Epidemiology, and Public Health (C-BEPH), University of Turin, Turin, Italy., Risch HA; Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT, USA., Ruebner M; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany., Sacerdote C; Unit of Epidemiology, Local Health Unit of Novara, Novara, Italy; Department of Health Sciences, University of Eastern Piedmont, Novara, Italy., Scott RJ; Division of Molecular Medicine, Pathology North, John Hunter Hospital, Newcastle, New South Wales, Australia; Discipline of Medical Genetics, School of Biomedical Sciences and Pharmacy, Faculty of Health, University of Newcastle, Callaghan, New South Wales, Australia; Hunter Medical Research Institute, John Hunter Hospital, Newcastle, New South Wales, Australia., Setiawan VW; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Shu XO; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA., Southey MC; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia; Department of Clinical Pathology, The University of Melbourne, Melbourne, Victoria, Australia., Tham E; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden; Clinical Genetics and Genomics, Karolinska University Hospital, Stockholm, Sweden., Tomlinson I; Department of Oncology, University of Oxford, Oxford, UK., Turman C; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Wentzensen N; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., Xu W; School of Public Health, Fudan University, Shanghai, China., Yu H; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI, USA., Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA., Spurdle AB; Population Health Program, QIMR Berghofer, Brisbane, Queensland, Australia., Yarden Y; Weizmann Institute of Science, Rehovot, Israel., Mägi R; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Hillemanns P; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Glubb DM; Cancer Research Program, QIMR Berghofer, Brisbane, Queensland, Australia; School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia., Dörk T; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany. Electronic address: Doerk.Thilo@mh-hannover.de., O'Mara TA; Cancer Research Program, QIMR Berghofer, Brisbane, Queensland, Australia; School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia. Electronic address: Tracy.OMara@qimrb.edu.au.
Corporate Authors: Estonian Biobank Research Team; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia.
Source: EBioMedicine [EBioMedicine] 2025 Aug; Vol. 118, pp. 105830. Date of Electronic Publication: 2025 Jul 08.
Publication Type: Journal Article; Meta-Analysis
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2352-3964
DOI:10.1016/j.ebiom.2025.105830