Cryptic variation fuels plant phenotypic change through hierarchical epistasis.

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Title: Cryptic variation fuels plant phenotypic change through hierarchical epistasis.
Authors: Zebell SG; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.; Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Martí-Gómez C; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Fitzgerald B; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.; Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Cunha CP; Department of Plant and Environmental Sciences, Weizmann Institute of Science, Rehovot, Israel., Lach M; Department of Plant and Environmental Sciences, Weizmann Institute of Science, Rehovot, Israel., Seman BM; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.; Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Hendelman A; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.; Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Sretenovic S; Department of Plant Science and Landscape Architecture, University of Maryland, College Park, MD, USA.; Stanford Genome Technology Center, School of Medicine, Stanford University, Palo Alto, CA, USA., Qi Y; Department of Plant Science and Landscape Architecture, University of Maryland, College Park, MD, USA., Bartlett M; Sainsbury Laboratory Cambridge University (SLCU), Cambridge, UK., Eshed Y; Department of Plant and Environmental Sciences, Weizmann Institute of Science, Rehovot, Israel. yuval.eshed@weizmann.ac.il., McCandlish DM; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA. mccandlish@cshl.edu., Lippman ZB; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA. lippman@cshl.edu.; Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA. lippman@cshl.edu.
Source: Nature [Nature] 2025 Aug; Vol. 644 (8078), pp. 984-992. Date of Electronic Publication: 2025 Jul 09.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-4687
DOI:10.1038/s41586-025-09243-0