Image-Derived Blood Normalization of Antibody-Based TREM2 PET in Mouse Models of Amyloidosis and Myocardial Infarction.

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Title: Image-Derived Blood Normalization of Antibody-Based TREM2 PET in Mouse Models of Amyloidosis and Myocardial Infarction.
Authors: Schaefer R; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany., Kunze LH; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany., Haertel M; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany., Zhu Y; Institute of Surgical Research at the Walter-Brendel-Centre of Experimental Medicine, University Hospital, LMU Munich, Munich, Germany., Schlepckow K; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany., Willem M; Chair of Metabolic Biochemistry, Biomedical Center (BMC), Faculty of Medicine, LMU Munich, Munich, Germany., Bartos LM; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany., Palumbo G; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany., Tomas L; Department of Medicine I, LMU University Hospital, LMU Munich, Munich, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany., Schulz C; Department of Medicine I, LMU University Hospital, LMU Munich, Munich, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.; Department of Immunopharmacology, Mannheim Institute for Innate Immunoscience (MI3), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Massberg S; Department of Medicine I, LMU University Hospital, LMU Munich, Munich, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany., Werner RA; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany.; Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland., Fischer M; Department of Medicine I, LMU University Hospital, LMU Munich, Munich, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany., Xia D; Denali Therapeutics Inc., South San Francisco, California., Monroe KM; Denali Therapeutics Inc., South San Francisco, California., Haass C; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Chair of Metabolic Biochemistry, Biomedical Center (BMC), Faculty of Medicine, LMU Munich, Munich, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany; and., Brendel M; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany.; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany; and.; German Cancer Consortium (DKTK), Partner Site Munich, German Cancer Research Center, Heidelberg, Germany., Lindner S; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany; simon.lindner@med.uni-muenchen.de.; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany; and.
Source: Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2025 Sep 02; Vol. 66 (9), pp. 1419-1424. Date of Electronic Publication: 2025 Sep 02.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Society of Nuclear Medicine Country of Publication: United States NLM ID: 0217410 Publication Model: Electronic Cited Medium: Internet ISSN: 1535-5667 (Electronic) Linking ISSN: 01615505 NLM ISO Abbreviation: J Nucl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Image-Derived Blood Normalization of Antibody-Based TREM2 PET in Mouse Models of Amyloidosis and Myocardial Infarction.
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  Data: <searchLink fieldCode="AU" term="%22Schaefer+R%22">Schaefer R</searchLink>; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Kunze+LH%22">Kunze LH</searchLink>; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Haertel+M%22">Haertel M</searchLink>; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Zhu+Y%22">Zhu Y</searchLink>; Institute of Surgical Research at the Walter-Brendel-Centre of Experimental Medicine, University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Schlepckow+K%22">Schlepckow K</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Willem+M%22">Willem M</searchLink>; Chair of Metabolic Biochemistry, Biomedical Center (BMC), Faculty of Medicine, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Bartos+LM%22">Bartos LM</searchLink>; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Palumbo+G%22">Palumbo G</searchLink>; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Tomas+L%22">Tomas L</searchLink>; Department of Medicine I, LMU University Hospital, LMU Munich, Munich, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Schulz+C%22">Schulz C</searchLink>; Department of Medicine I, LMU University Hospital, LMU Munich, Munich, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.; Department of Immunopharmacology, Mannheim Institute for Innate Immunoscience (MI3), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Massberg+S%22">Massberg S</searchLink>; Department of Medicine I, LMU University Hospital, LMU Munich, Munich, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Werner+RA%22">Werner RA</searchLink>; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany.; Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Fischer+M%22">Fischer M</searchLink>; Department of Medicine I, LMU University Hospital, LMU Munich, Munich, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Xia+D%22">Xia D</searchLink>; Denali Therapeutics Inc., South San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Monroe+KM%22">Monroe KM</searchLink>; Denali Therapeutics Inc., South San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Haass+C%22">Haass C</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Chair of Metabolic Biochemistry, Biomedical Center (BMC), Faculty of Medicine, LMU Munich, Munich, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany; and.<br /><searchLink fieldCode="AU" term="%22Brendel+M%22">Brendel M</searchLink>; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany.; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany; and.; German Cancer Consortium (DKTK), Partner Site Munich, German Cancer Research Center, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Lindner+S%22">Lindner S</searchLink>; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany; simon.lindner@med.uni-muenchen.de.; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany; and.
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  Data: <searchLink fieldCode="JN" term="%220217410%22">Journal of nuclear medicine : official publication, Society of Nuclear Medicine</searchLink> [J Nucl Med] 2025 Sep 02; Vol. 66 (9), pp. 1419-1424. <i>Date of Electronic Publication: </i>2025 Sep 02.
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