Genome sequencing is critical for forecasting outcomes following congenital cardiac surgery.

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Bibliographic Details
Title: Genome sequencing is critical for forecasting outcomes following congenital cardiac surgery.
Authors: Watkins WS; Department of Human Genetics, University of Utah, Salt Lake City, UT, 84112, USA., Hernandez EJ; Department of Biomedical Informatics, University of Utah, Salt Lake City, UT, 84108, USA., Miller TA; Department of Pediatrics, Maine Medical Center, Portland, ME, USA., Blue NR; Department of Obstetrics and Gynecology, University of Utah, Salt Lake City, UT, 84112, USA., Zimmerman RM; Department of Biomedical Informatics, University of Utah, Salt Lake City, UT, 84108, USA., Griffiths ER; Pediatric Cardiothoracic Surgery, University of Utah, Salt Lake City, UT, USA., Frise E; Fabric Genomics Inc, Oakland, CA, 94612, USA., Bernstein D; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, 94305, USA., Boskovski MT; Department of Surgery, University of California, San Francisco, CA, 94143, USA., Brueckner M; Department of Pediatrics, Yale University School of Medicine, New Haven, CT, 06510, USA.; Department of Genetics, Yale University School of Medicine, New Haven, CT, 06510, USA., Chung WK; Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, 02115, USA., Gaynor JW; Division of Cardiothoracic Surgery, Department of Surgery, Children's Hospital of Philadelphia, and the Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Gelb BD; Mindich Child Health and Development Institute and Departments of Pediatrics and Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Goldmuntz E; Division of Cardiology, Children's Hospital of Philadelphia, Department of Pediatrics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Gruber PJ; Department of Surgery, Yale University, New Haven, CT, USA., Newburger JW; Department of Cardiology, Boston Children's Hospital, and Department of Pediatrics, Harvard Medical School, Boston, MA, 02115, USA., Roberts AE; Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, 02115, USA.; Department of Cardiology, Boston Children's Hospital, and Department of Pediatrics, Harvard Medical School, Boston, MA, 02115, USA., Morton SU; Division of Newborn Medicine, Department of Medicine, Boston Children's Hospital, Boston, MA, USA., Mayer JE Jr; Department of Cardiovascular Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA, 02115, USA., Seidman CE; Departments of Genetics and Medicine, Harvard Medical School, Boston, MA, 02115, USA.; Cardiovascular Division, Massachusetts General Brigham, Boston, MA, 02115, USA., Seidman JG; Departments of Genetics and Medicine, Harvard Medical School, Boston, MA, 02115, USA., Shen Y; Departments of Systems Biology and Biomedical Informatics, Columbia University, New York, NY, 10032, USA., Wagner M; Division of Biomedical Informatics, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Yost HJ; Molecular Medicine Program, University of Utah, Salt Lake City, UT, 84112, USA., Yandell M; Department of Human Genetics, University of Utah, Salt Lake City, UT, 84112, USA. myandell@genetics.utah.edu., Tristani-Firouzi M; Nora Eccles Harrison Cardiovascular Research and Training Institute, and Division of Pediatric Cardiology, Salt Lake City, UT, 84108, USA. Martin.Tristani@utah.edu.
Source: Nature communications [Nat Commun] 2025 Jul 10; Vol. 16 (1), pp. 6365. Date of Electronic Publication: 2025 Jul 10.
Publication Type: Journal Article; Observational Study
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2041-1723
DOI:10.1038/s41467-025-61625-0