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Naltrexone reduces bleomycin-induced lung fibrosis in rats by attenuating fibrosis, inflammation, oxidative stress, and extracellular matrix remodeling.

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Title: Naltrexone reduces bleomycin-induced lung fibrosis in rats by attenuating fibrosis, inflammation, oxidative stress, and extracellular matrix remodeling.
Authors: Mohammadi Hamaneh A; Experimental Medicine Research Center, Tehran University of Medical Sciences (TUMS), Tehran, Iran; Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran., Nejati F; Experimental Medicine Research Center, Tehran University of Medical Sciences (TUMS), Tehran, Iran; Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran., Teymoori Masuleh M; Experimental Medicine Research Center, Tehran University of Medical Sciences (TUMS), Tehran, Iran; Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran., Manavi MA; Experimental Medicine Research Center, Tehran University of Medical Sciences (TUMS), Tehran, Iran., Kazemzadeh H; Experimental Medicine Research Center, Tehran University of Medical Sciences (TUMS), Tehran, Iran., Shafaroodi H; Experimental Medicine Research Center, Tehran University of Medical Sciences (TUMS), Tehran, Iran; Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: Hshafaroodi@gmail.com., Tavangar SM; Department of Pathology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran; Department of Intensive Care, Imam Khomeini Hospital Complex, TUMS, Tehran, Iran., Dehpour AR; Experimental Medicine Research Center, Tehran University of Medical Sciences (TUMS), Tehran, Iran; Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: Dehpour@yahoo.com.
Source: International immunopharmacology [Int Immunopharmacol] 2025 Sep 23; Vol. 162, pp. 115182. Date of Electronic Publication: 2025 Jul 10.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Naltrexone reduces bleomycin-induced lung fibrosis in rats by attenuating fibrosis, inflammation, oxidative stress, and extracellular matrix remodeling.
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  Data: <searchLink fieldCode="AU" term="%22Mohammadi+Hamaneh+A%22">Mohammadi Hamaneh A</searchLink>; Experimental Medicine Research Center, Tehran University of Medical Sciences (TUMS), Tehran, Iran; Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Nejati+F%22">Nejati F</searchLink>; Experimental Medicine Research Center, Tehran University of Medical Sciences (TUMS), Tehran, Iran; Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Teymoori+Masuleh+M%22">Teymoori Masuleh M</searchLink>; Experimental Medicine Research Center, Tehran University of Medical Sciences (TUMS), Tehran, Iran; Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Manavi+MA%22">Manavi MA</searchLink>; Experimental Medicine Research Center, Tehran University of Medical Sciences (TUMS), Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Kazemzadeh+H%22">Kazemzadeh H</searchLink>; Experimental Medicine Research Center, Tehran University of Medical Sciences (TUMS), Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Shafaroodi+H%22">Shafaroodi H</searchLink>; Experimental Medicine Research Center, Tehran University of Medical Sciences (TUMS), Tehran, Iran; Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: Hshafaroodi@gmail.com.<br /><searchLink fieldCode="AU" term="%22Tavangar+SM%22">Tavangar SM</searchLink>; Department of Pathology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran; Department of Intensive Care, Imam Khomeini Hospital Complex, TUMS, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Dehpour+AR%22">Dehpour AR</searchLink>; Experimental Medicine Research Center, Tehran University of Medical Sciences (TUMS), Tehran, Iran; Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: Dehpour@yahoo.com.
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  Data: <searchLink fieldCode="JN" term="%22100965259%22">International immunopharmacology</searchLink> [Int Immunopharmacol] 2025 Sep 23; Vol. 162, pp. 115182. <i>Date of Electronic Publication: </i>2025 Jul 10.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>100965259 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1878-1705 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215675769%22">15675769 </searchLink><i>NLM ISO Abbreviation: </i>Int Immunopharmacol <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.intimp.2025.115182
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