Inhibition of FOXM1 Synergizes with BH3 Mimetics Venetoclax and Sonrotoclax in Killing Multiple Myeloma Cells through Repressing MYC Pathway.
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| Title: | Inhibition of FOXM1 Synergizes with BH3 Mimetics Venetoclax and Sonrotoclax in Killing Multiple Myeloma Cells through Repressing MYC Pathway. |
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| Authors: | Wen Z; Center for Precision Medicine Research, Marshfield Clinic Research Institute, Marshfield Clinic Health System, Marshfield, WI, 54449, USA., Wang Y; McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, WI, 53705, USA., Fox KC; UW Carbone Cancer Center Flow Cytometry Laboratory, University of Wisconsin-Madison, Madison, WI, 53705, USA., Bissonnette AM; Center for Precision Medicine Research, Marshfield Clinic Research Institute, Marshfield Clinic Health System, Marshfield, WI, 54449, USA.; Integrated Research and Development Lab, Marshfield Clinic Research Institute, Marshfield Clinic Health System, Marshfield, WI, 54449, USA., Moat LF; Center for Precision Medicine Research, Marshfield Clinic Research Institute, Marshfield Clinic Health System, Marshfield, WI, 54449, USA., Kitchner TE; Center for Precision Medicine Research, Marshfield Clinic Research Institute, Marshfield Clinic Health System, Marshfield, WI, 54449, USA., Springstroh K; Department of Pathology, Marshfield Medical Center, Marshfield Clinic Health System, Marshfield, WI, 54449, USA., Kim SH; Department of Chemistry, Department of Molecular and Integrative Physiology, Cancer Center at Illinois, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA., Sheerar DS; UW Carbone Cancer Center Flow Cytometry Laboratory, University of Wisconsin-Madison, Madison, WI, 53705, USA., Tanawattanacharoen P; Cancer Care and Research Center, Marshfield Medical Center, Marshfield Clinic Health System, Marshfield, WI, 54449, USA., Leon CA; Cancer Care and Research Center, Marshfield Medical Center, Marshfield Clinic Health System, Marshfield, WI, 54449, USA., Fagbemi SO; Cancer Care and Research Center, Marshfield Medical Center, Marshfield Clinic Health System, Marshfield, WI, 54449, USA., Katzenellenbogen JA; Department of Chemistry, Department of Molecular and Integrative Physiology, Cancer Center at Illinois, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA., Hebbring SJ; Center for Precision Medicine Research, Marshfield Clinic Research Institute, Marshfield Clinic Health System, Marshfield, WI, 54449, USA., Katzenellenbogen BS; Department of Chemistry, Department of Molecular and Integrative Physiology, Cancer Center at Illinois, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA., Janz S; Department of Medicine, Cancer Center-Froedtert Hospital, Medical College of Wisconsin, Milwaukee, WI, 53226, USA., Onitilo AA; Cancer Care and Research Center, Marshfield Medical Center, Marshfield Clinic Health System, Marshfield, WI, 54449, USA. |
| Source: | Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2025 Oct; Vol. 12 (37), pp. e08822. Date of Electronic Publication: 2025 Jul 14. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844 (Electronic) Linking ISSN: 21983844 NLM ISO Abbreviation: Adv Sci (Weinh) Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2198-3844 |
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| DOI: | 10.1002/advs.202508822 |
