MYH11 rare variant augments aortic growth and induces cardiac hypertrophy and heart failure with pressure overload.

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Title: MYH11 rare variant augments aortic growth and induces cardiac hypertrophy and heart failure with pressure overload.
Authors: Zhou Z; Division of Medical Genetics, Department of Internal Medicine, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, Texas, United States of America., Hughes K; Division of Medical Genetics, Department of Internal Medicine, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, Texas, United States of America., Saif N; Division of Medical Genetics, Department of Internal Medicine, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, Texas, United States of America.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America., Kim H; Department Kinesiology & Sport Management, Texas Tech University, Lubbock, Texas, United States of America., Massett MP; Department Kinesiology & Sport Management, Texas Tech University, Lubbock, Texas, United States of America., Zheng M; Department of Pediatrics, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, Texas, United States of America., Cecchi AC; Division of Medical Genetics, Department of Internal Medicine, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, Texas, United States of America., Guo D; Division of Medical Genetics, Department of Internal Medicine, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, Texas, United States of America., Murdock DR; Division of Medical Genetics, Department of Internal Medicine, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, Texas, United States of America., Pan P; Division of Medical Genetics, Department of Internal Medicine, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, Texas, United States of America., Clinton JS; Division of Medical Genetics, Department of Internal Medicine, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, Texas, United States of America., Wang J; Department of Pediatrics, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, Texas, United States of America., Greally JM; Department of Genetics, Albert Einstein College of Medicine, New York, New York, United States of America., Milewicz DM; Division of Medical Genetics, Department of Internal Medicine, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, Texas, United States of America.
Source: PLoS genetics [PLoS Genet] 2025 Jul 14; Vol. 21 (7), pp. e1011394. Date of Electronic Publication: 2025 Jul 14 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1553-7404
DOI:10.1371/journal.pgen.1011394