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Prevention of extubation failure in neurocritical care patients with residual disorder of consciousness: the Brain-Injured Patients Extubation Readiness (BIPER) study protocol for a stepped-wedge cluster-randomised controlled trial.

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Title: Prevention of extubation failure in neurocritical care patients with residual disorder of consciousness: the Brain-Injured Patients Extubation Readiness (BIPER) study protocol for a stepped-wedge cluster-randomised controlled trial.
Authors: Chabanne R; Department of Perioperative Medicine, Centre Hospitalier Universitaire de Clermont-Ferrand, Clermont-Ferrand, France rchabanne@chu-clermontferrand.fr., Godet T; Department of Perioperative Medicine, Centre Hospitalier Universitaire de Clermont-Ferrand, Clermont-Ferrand, France.; Department of Healthcare Simulation and NEURO-DOL, UMR 1107, INSERM, Université Clermont Auvergne Institut Sciences de la Vie Santé Agronomie Environnement, Clermont-Ferrand, France., Andanson B; Department of Perioperative Medicine, Centre Hospitalier Universitaire de Clermont-Ferrand, Clermont-Ferrand, France., Borrel P; Department of Perioperative Medicine, Centre Hospitalier Universitaire de Clermont-Ferrand, Clermont-Ferrand, France., Astier L; Department of Perioperative Medicine, Centre Hospitalier Universitaire de Clermont-Ferrand, Clermont-Ferrand, France., Caumon E; Department of Perioperative Medicine, Centre Hospitalier Universitaire de Clermont-Ferrand, Clermont-Ferrand, France., Bourguignon N; Department of Clinical Research and Innovation (DRCI), Centre Hospitalier Universitaire de Clermont-Ferrand, Clermont-Ferrand, France., Laclautre L; Department of Clinical Research and Innovation (DRCI), Centre Hospitalier Universitaire de Clermont-Ferrand, Clermont-Ferrand, France., Morand D; Department of Clinical Research and Innovation (DRCI), Centre Hospitalier Universitaire de Clermont-Ferrand, Clermont-Ferrand, France., De Jong A; Department of Anaesthesiology and Critical Care Medicine B (DAR B), Centre Hospitalier Universitaire de Montpellier, Montpellier, France.; PhyMed Exp, Université de Montpellier, INSERM U1046, Montpellier, France., Futier E; Department of Perioperative Medicine, Centre Hospitalier Universitaire de Clermont-Ferrand, Clermont-Ferrand, France.; iGReD, CNRS, INSERM, Université Clermont Auvergne, Clermont-Ferrand, France., Constantin JM; Department of Anesthesiology and Critical Care, Centre Hospitalier Universitaire Pitié Salpêtrière, Paris, France.; GRC 29, AP-HP, DMU DREAM, Sorbonne University, Paris, France., Pereira B; Biostatistics and Data Management Unit, Department of Clinical Research and Innovation, Centre Hospitalier Universitaire de Clermont-Ferrand, Clermont-Ferrand, France., Jabaudon M; Department of Perioperative Medicine, Centre Hospitalier Universitaire de Clermont-Ferrand, Clermont-Ferrand, France.; iGReD, CNRS, INSERM, Université Clermont Auvergne, Clermont-Ferrand, France.
Source: BMJ open [BMJ Open] 2025 Jul 13; Vol. 15 (7), pp. e104897. Date of Electronic Publication: 2025 Jul 13.
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2044-6055
DOI:10.1136/bmjopen-2025-104897